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CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation.
Hsu, Jingmei; Huang, Hsuan-Ting; Lee, Chung-Tsai; Choudhuri, Avik; Wilson, Nicola K; Abraham, Brian J; Moignard, Victoria; Kucinski, Iwo; Yu, Shuqian; Hyde, R Katherine; Tober, Joanna; Cai, Xiongwei; Li, Yan; Guo, Yalin; Yang, Song; Superdock, Michael; Trompouki, Eirini; Calero-Nieto, Fernando J; Ghamari, Alireza; Jiang, Jing; Gao, Peng; Gao, Long; Nguyen, Vy; Robertson, Anne L; Durand, Ellen M; Kathrein, Katie L; Aifantis, Iannis; Gerber, Scott A; Tong, Wei; Tan, Kai; Cantor, Alan B; Zhou, Yi; Liu, P Paul; Young, Richard A; Göttgens, Berthold; Speck, Nancy A; Zon, Leonard I.
Affiliation
  • Hsu J; Division of Hematology/Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104.
  • Huang HT; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Lee CT; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104.
  • Choudhuri A; Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Wilson NK; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Abraham BJ; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104.
  • Moignard V; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138.
  • Kucinski I; Cambridge Institute for Medical Research, Department of Haematology, Wellcome Trust/Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom CB2 OXY.
  • Yu S; Whitehead Institute for Biomedical Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.
  • Hyde RK; Cambridge Institute for Medical Research, Department of Haematology, Wellcome Trust/Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom CB2 OXY.
  • Tober J; Cambridge Institute for Medical Research, Department of Haematology, Wellcome Trust/Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom CB2 OXY.
  • Cai X; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Li Y; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.
  • Guo Y; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Yang S; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104.
  • Superdock M; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Trompouki E; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104.
  • Calero-Nieto FJ; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104.
  • Ghamari A; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104.
  • Jiang J; Department of Microbiology and Immunology, Geisel School of Medicine, Lebanon, NH 03756.
  • Gao P; Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Gao L; Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Nguyen V; Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Robertson AL; Cambridge Institute for Medical Research, Department of Haematology, Wellcome Trust/Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom CB2 OXY.
  • Durand EM; Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Kathrein KL; Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
  • Aifantis I; Division of Oncology and Center for Childhood Cancer Research, Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
  • Gerber SA; Division of Oncology and Center for Childhood Cancer Research, Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
  • Tong W; Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Tan K; Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Cantor AB; Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Zhou Y; Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Liu PP; Department of Pathology and Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016.
  • Young RA; Department of Genetics, Geisel School of Medicine, Lebanon, NH 03756.
  • Göttgens B; Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
  • Speck NA; Division of Oncology and Center for Childhood Cancer Research, Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
  • Zon LI; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Proc Natl Acad Sci U S A ; 117(38): 23626-23635, 2020 09 22.
Article de En | MEDLINE | ID: mdl-32883883

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protéines de liaison à l'ADN / Sous-unité alpha 2 du facteur CBF / Hématopoïèse Limites: Animals / Female / Humans / Male Langue: En Journal: Proc Natl Acad Sci U S A Année: 2020 Type de document: Article

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protéines de liaison à l'ADN / Sous-unité alpha 2 du facteur CBF / Hématopoïèse Limites: Animals / Female / Humans / Male Langue: En Journal: Proc Natl Acad Sci U S A Année: 2020 Type de document: Article