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Aframomum melegueta secondary metabolites exhibit polypharmacology against SARS-CoV-2 drug targets: in vitro validation of furin inhibition.
Omotuyi, I Olaposi; Nash, Oyekanmi; Ajiboye, Basiru O; Olumekun, Victor O; Oyinloye, Babatunji E; Osuntokun, Oludare T; Olonisakin, Adebisi; Ajayi, A Olajide; Olusanya, Olasehinde; Akomolafe, Funmilola S; Adelakun, Niyi.
Affiliation
  • Omotuyi IO; Chemo-Genomics Research Unit, Department of Biochemistry, Adekunle Ajasin University, Akungba, Nigeria.
  • Nash O; Chemoinformatics Unit, Mols & Sims, Ado Ekiti, Nigeria.
  • Ajiboye BO; Center for Genomics Research and Innovation, National Biotechnology Development Agency, Abuja, Nigeria.
  • Olumekun VO; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado Ekiti, Nigeria.
  • Oyinloye BE; Department of Plant Science and Biotechnology, Adekunle Ajasin University, Akungba, Nigeria.
  • Osuntokun OT; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado Ekiti, Nigeria.
  • Olonisakin A; Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa, South Africa.
  • Ajayi AO; Department of Chemical Sciences, Adekunle Ajasin University, Akungba, Nigeria.
  • Olusanya O; Department of Chemical Sciences, Adekunle Ajasin University, Akungba, Nigeria.
  • Akomolafe FS; Department of Microbiology, Adekunle Ajasin University, Akungba, Nigeria.
  • Adelakun N; Department of Biochemistry, Faculty of Life Sciences, University of Benin, Benin City, Nigeria.
Phytother Res ; 35(2): 908-919, 2021 Feb.
Article de En | MEDLINE | ID: mdl-32964551
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Extraits de plantes / Zingiberaceae / Furine / SARS-CoV-2 / Traitements médicamenteux de la COVID-19 / Phytothérapie Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Phytother Res Sujet du journal: TERAPIAS COMPLEMENTARES Année: 2021 Type de document: Article Pays d'affiliation: Nigeria
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Extraits de plantes / Zingiberaceae / Furine / SARS-CoV-2 / Traitements médicamenteux de la COVID-19 / Phytothérapie Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Phytother Res Sujet du journal: TERAPIAS COMPLEMENTARES Année: 2021 Type de document: Article Pays d'affiliation: Nigeria