Ligand Incorporation into Protein Microcrystals for MicroED by On-Grid Soaking.

Martynowycz, Michael W; Gonen, Tamir

Martynowycz, Michael W; Gonen, Tamir.

Affiliation

Martynowycz MW; Department of Biological Chemistry, University of California Los Angeles, 615 Charles E Young Drive South, Los Angeles, CA 90095, USA; Department of Physiology, University of California Los Angeles, 615 Charles E Young Drive South, Los Angeles, CA 90095, USA; Howard Hughes Medical Institute, University of California Los Angeles, Los Angeles CA90095, USA.
Gonen T; Department of Biological Chemistry, University of California Los Angeles, 615 Charles E Young Drive South, Los Angeles, CA 90095, USA; Department of Physiology, University of California Los Angeles, 615 Charles E Young Drive South, Los Angeles, CA 90095, USA; Howard Hughes Medical Institute, University of California Los Angeles, Los Angeles CA90095, USA. Electronic address: tgonen@g.ucla.edu.

Structure ; 29(1): 88-95.e2, 2021 01 07.

Article de En | MEDLINE | ID: mdl-33007196

Sujet(s)
Mots clés

-SEM; MicroED; cryoelectron microscopy (cryo-EM); drug discovery; focused ion-beam (FIB); ligand soaking

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Endopeptidase K / Cryomicroscopie électronique / Microscopie électronique à transmission Langue: En Journal: Structure Sujet du journal: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Année: 2021 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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