Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers Rescue Memory Defects in <i>Drosophila</i>-Expressing Alzheimer's Disease-Related Transgenes Independently of the Canonical Renin Angiotensin System.

Lee, Shin-Hann; Gomes, Sarah M; Ghalayini, Judy; Iliadi, Konstantin G; Boulianne, Gabrielle L

Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers Rescue Memory Defects in Drosophila-Expressing Alzheimer's Disease-Related Transgenes Independently of the Canonical Renin Angiotensin System.

Lee, Shin-Hann; Gomes, Sarah M; Ghalayini, Judy; Iliadi, Konstantin G; Boulianne, Gabrielle L.

Affiliation

Lee SH; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, M5G 0A4, Toronto, ON, CA.
Gomes SM; Department of Molecular Genetics, University of Toronto, M5S 1A1, Toronto, ON, CA.
Ghalayini J; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, M5G 0A4, Toronto, ON, CA.
Iliadi KG; Institute of Medical Science, University of Toronto, M5S 1A1, Toronto, ON, CA.
Boulianne GL; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, M5G 0A4, Toronto, ON, CA.

eNeuro ; 7(6)2020.

Article de En | MEDLINE | ID: mdl-33060184

Sujet(s)
Mots clés

Alzheimer's disease; Drosophila; amyloid; memory; presenilin; renin angiotensin system

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protéines de Drosophila / Maladie d'Alzheimer Limites: Animals / Humans Langue: En Journal: ENeuro Année: 2020 Type de document: Article Pays d'affiliation: Canada Pays de publication: États-Unis d'Amérique

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