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Torin 2 Derivative, NCATS-SM3710, Has Potent Multistage Antimalarial Activity through Inhibition of P. falciparum Phosphatidylinositol 4-Kinase (Pf PI4KIIIß).
Krishnan, Karthik; Ziniel, Peter; Li, Hao; Huang, Xiuli; Hupalo, Daniel; Gombakomba, Nita; Guerrero, Sandra Mendoza; Dotrang, Thoai; Lu, Xiao; Caridha, Diana; Sternberg, Anna R; Hughes, Emma; Sun, Wei; Bargieri, Daniel Y; Roepe, Paul D; Sciotti, Richard J; Wilkerson, Matthew D; Dalgard, Clifton L; Tawa, Gregory J; Wang, Amy Q; Xu, Xin; Zheng, Wei; Sanderson, Philip E; Huang, Wenwei; Williamson, Kim C.
Affiliation
  • Krishnan K; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
  • Ziniel P; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
  • Li H; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
  • Huang X; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
  • Hupalo D; Collaborative Health Initiative Research Program, Department of Anatomy, Physiology and Genetics Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
  • Gombakomba N; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
  • Guerrero SM; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
  • Dotrang T; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
  • Lu X; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
  • Caridha D; Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Sternberg AR; Departments of Chemistry and of Biochemistry, Cellular and Molecular Biology, Georgetown University, Washington, DC 20057, United States.
  • Hughes E; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
  • Sun W; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
  • Bargieri DY; Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, 05508, Brazil.
  • Roepe PD; Departments of Chemistry and of Biochemistry, Cellular and Molecular Biology, Georgetown University, Washington, DC 20057, United States.
  • Sciotti RJ; Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Wilkerson MD; Collaborative Health Initiative Research Program, Department of Anatomy, Physiology and Genetics Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
  • Dalgard CL; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
  • Tawa GJ; The American Genome Center, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
  • Wang AQ; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
  • Xu X; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
  • Zheng W; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
  • Sanderson PE; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
  • Huang W; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
  • Williamson KC; National Center for Advancing Translational Science, National Institutes of Health, Rockville, Maryland 20892, United States.
ACS Pharmacol Transl Sci ; 3(5): 948-964, 2020 Oct 09.
Article de En | MEDLINE | ID: mdl-33073193
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: ACS Pharmacol Transl Sci Année: 2020 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: ACS Pharmacol Transl Sci Année: 2020 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique