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High tumor mutational burden and T-cell activation are associated with long-term response to anti-PD1 therapy in Lynch syndrome recurrent glioblastoma patient.
Anghileri, Elena; Di Ianni, Natalia; Paterra, Rosina; Langella, Tiziana; Zhao, Junfei; Eoli, Marica; Patanè, Monica; Pollo, Bianca; Cuccarini, Valeria; Iavarone, Antonio; Rabadan, Raul; Finocchiaro, Gaetano; Pellegatta, Serena.
Affiliation
  • Anghileri E; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy. elena.anghileri@istituto-besta.it.
  • Di Ianni N; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.
  • Paterra R; Laboratory of Immunotherapy of Brain Tumors, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
  • Langella T; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.
  • Zhao J; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.
  • Eoli M; Institute for Cancer Genetics, University of Columbia, New York, NY, USA.
  • Patanè M; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.
  • Pollo B; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133, Milan, Italy.
  • Cuccarini V; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133, Milan, Italy.
  • Iavarone A; Neuroradiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133, Milan, Italy.
  • Rabadan R; Institute for Cancer Genetics, Department of Neurology and Pathology, Columbia University Medical Center, New York, NY, USA.
  • Finocchiaro G; Institute for Cancer Genetics, University of Columbia, New York, NY, USA.
  • Pellegatta S; Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy.
Cancer Immunol Immunother ; 70(3): 831-842, 2021 Mar.
Article de En | MEDLINE | ID: mdl-33140187

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lymphocytes T / Tumeurs colorectales héréditaires sans polypose / Marqueurs biologiques tumoraux / Glioblastome / Mutation Type d'étude: Diagnostic_studies / Risk_factors_studies Limites: Adult / Female / Humans Langue: En Journal: Cancer Immunol Immunother Sujet du journal: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Année: 2021 Type de document: Article Pays d'affiliation: Italie Pays de publication: Allemagne

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lymphocytes T / Tumeurs colorectales héréditaires sans polypose / Marqueurs biologiques tumoraux / Glioblastome / Mutation Type d'étude: Diagnostic_studies / Risk_factors_studies Limites: Adult / Female / Humans Langue: En Journal: Cancer Immunol Immunother Sujet du journal: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Année: 2021 Type de document: Article Pays d'affiliation: Italie Pays de publication: Allemagne