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Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release.
Simon, Jillian N; Vrellaku, Besarte; Monterisi, Stefania; Chu, Sandy M; Rawlings, Nadiia; Lomas, Oliver; Marchal, Gerard A; Waithe, Dominic; Syeda, Fahima; Gajendragadkar, Parag R; Jayaram, Raja; Sayeed, Rana; Channon, Keith M; Fabritz, Larissa; Swietach, Pawel; Zaccolo, Manuela; Eaton, Philip; Casadei, Barbara.
Affiliation
  • Simon JN; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (J.N.S., B.V., S.M.C., N.R., O.L., G.A.M., P.R.G., R.J., K.M.C., B.C.), University of Oxford, United Kingdom.
  • Vrellaku B; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (J.N.S., B.V., S.M.C., N.R., O.L., G.A.M., P.R.G., R.J., K.M.C., B.C.), University of Oxford, United Kingdom.
  • Monterisi S; Department of Physiology, Anatomy and Genetics (S.M., P.S., M.Z.), University of Oxford, United Kingdom.
  • Chu SM; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (J.N.S., B.V., S.M.C., N.R., O.L., G.A.M., P.R.G., R.J., K.M.C., B.C.), University of Oxford, United Kingdom.
  • Rawlings N; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (J.N.S., B.V., S.M.C., N.R., O.L., G.A.M., P.R.G., R.J., K.M.C., B.C.), University of Oxford, United Kingdom.
  • Lomas O; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (J.N.S., B.V., S.M.C., N.R., O.L., G.A.M., P.R.G., R.J., K.M.C., B.C.), University of Oxford, United Kingdom.
  • Marchal GA; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (J.N.S., B.V., S.M.C., N.R., O.L., G.A.M., P.R.G., R.J., K.M.C., B.C.), University of Oxford, United Kingdom.
  • Waithe D; Wolfson Imaging Centre, Weatherall Institute of Molecular Medicine (D.W.), University of Oxford, United Kingdom.
  • Syeda F; Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom (F.S., L.F.).
  • Gajendragadkar PR; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (J.N.S., B.V., S.M.C., N.R., O.L., G.A.M., P.R.G., R.J., K.M.C., B.C.), University of Oxford, United Kingdom.
  • Jayaram R; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (J.N.S., B.V., S.M.C., N.R., O.L., G.A.M., P.R.G., R.J., K.M.C., B.C.), University of Oxford, United Kingdom.
  • Sayeed R; Cardiothoracic Surgery, Oxford Heart Centre, Oxford University Hospitals National Health Service Foundation Trust, United Kingdom (R.S.).
  • Channon KM; Division of Cardiovascular Medicine, Radcliffe Department of Medicine (J.N.S., B.V., S.M.C., N.R., O.L., G.A.M., P.R.G., R.J., K.M.C., B.C.), University of Oxford, United Kingdom.
  • Fabritz L; Institute of Cardiovascular Sciences, University of Birmingham, United Kingdom (F.S., L.F.).
  • Swietach P; Department of Cardiology, University Hospitals Birmingham, United Kingdom (L.F.).
  • Zaccolo M; Department of Physiology, Anatomy and Genetics (S.M., P.S., M.Z.), University of Oxford, United Kingdom.
  • Eaton P; Department of Physiology, Anatomy and Genetics (S.M., P.S., M.Z.), University of Oxford, United Kingdom.
  • Casadei B; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, United Kingdom (P.E.).
Circulation ; 143(5): 449-465, 2021 02 02.
Article de En | MEDLINE | ID: mdl-33185461
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lésion de reperfusion myocardique / Calcium / Cyclic AMP-Dependent Protein Kinases / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit Limites: Animals / Humans Langue: En Journal: Circulation Année: 2021 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lésion de reperfusion myocardique / Calcium / Cyclic AMP-Dependent Protein Kinases / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit Limites: Animals / Humans Langue: En Journal: Circulation Année: 2021 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: États-Unis d'Amérique