The short term effect of trehalose and different doses of sodium hyaluronate on anterior corneal aberrations in dry eye patients.
Cutan Ocul Toxicol
; 40(1): 14-20, 2021 Mar.
Article
de En
| MEDLINE
| ID: mdl-33342322
ABSTRACT
AIM:
To evaluate the short-term effect of 0.15% sodium hyaluronate (SH), 0.20% SH, and Trehalose + 0.15% SH on anterior corneal aberrations in dry eye patients.METHODS:
76 eyes of 76 dry eye patients were divided into three groups. Non-preserved 1.5 mg/mL SH was administered in group 1, non-preserved 2.0 mg/mL SH was administered in group 2, and non-preserved trehalose 30 mg/mL and 1.5 mg/mL SH was administered in group 3. Aberrometry measurements were performed before and 10 min after application of the artificial tear drop. Using the Pentacam Scheimpflug imaging system, total root mean square (RMS), lower-order aberration (LOA), higher-order aberrations (HOAs), spherical aberration (SA), trefoil, and coma aberrations were investigated.RESULTS:
In each group; the RMS of total, LOA, HOAs, and spherical aberration were significantly decreased after the artificial drop instillation, compared with those of them at baseline; and in groups 1 and 2, vertical trefoil term was also significantly increased, compared with those of them at baseline. According to intergroup analyzes, there was no significant outcome.CONCLUSIONS:
It was observed that three artificial tears reduced the anterior corneal aberrations, in a 10-min period. The short-term effect of three artificial tears on the anterior corneal aberration was similar.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tréhalose
/
Syndromes de l'oeil sec
/
Gouttes oculaires lubrifiantes
/
Acide hyaluronique
Type d'étude:
Diagnostic_studies
/
Observational_studies
Limites:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Cutan Ocul Toxicol
Sujet du journal:
DERMATOLOGIA
/
OFTALMOLOGIA
/
TOXICOLOGIA
Année:
2021
Type de document:
Article
Pays d'affiliation:
Turquie