HMGB1 suppress the expression of IL-35 by regulating Naïve CD4+ T cell differentiation and aggravating Caspase-11-dependent pyroptosis in acute lung injury.

Xie, Ke; Chen, Yan-Qing; Chai, Yu-Sen; Lin, Shi-Hui; Wang, Chuan-Jiang; Xu, Fang

Xie, Ke; Chen, Yan-Qing; Chai, Yu-Sen; Lin, Shi-Hui; Wang, Chuan-Jiang; Xu, Fang.

Affiliation

Xie K; Department of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chen YQ; Department of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chai YS; Department of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Lin SH; Department of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wang CJ; Department of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: wangchuanjiang@cqmu.edu.cn.
Xu F; Department of Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: xufang828@126.com.

Int Immunopharmacol ; 91: 107295, 2021 Feb.

Article de En | MEDLINE | ID: mdl-33360086

Sujet(s)
Mots clés

Acute lung injury; Caspase-11; High-mobility group box 1; Interlukin-35; Pyroptosis; Regulatory T cell

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: / Lymphocytes T CD4/ / Différenciation cellulaire / Interleukines / Protéine HMGB1 / Caspases initiatrices / Lésion pulmonaire aigüe / Pyroptose / Poumon Limites: Animals Langue: En Journal: Int Immunopharmacol Sujet du journal: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Année: 2021 Type de document: Article Pays d'affiliation: Chine Pays de publication: Pays-Bas

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