<i>In-silico</i> identification of potential inhibitors targeting the DNA binding domain of estrogen receptor &#945; for the treatment of hormone therapy-resistant breast cancer.

Bouricha, El Mehdi; Hakmi, Mohammed; Akachar, Jihane; Zouaidia, Fouad; Ibrahimi, Azeddine

In-silico identification of potential inhibitors targeting the DNA binding domain of estrogen receptor α for the treatment of hormone therapy-resistant breast cancer.

Bouricha, El Mehdi; Hakmi, Mohammed; Akachar, Jihane; Zouaidia, Fouad; Ibrahimi, Azeddine.

Affiliation

Bouricha EM; Medical Biotechnology Laboratory (MedBiotech), Rabat Medical & Pharmacy School, Mohammed Vth University in Rabat, Morocco.
Hakmi M; Medical Biotechnology Laboratory (MedBiotech), Rabat Medical & Pharmacy School, Mohammed Vth University in Rabat, Morocco.
Akachar J; Medical Biotechnology Laboratory (MedBiotech), Rabat Medical & Pharmacy School, Mohammed Vth University in Rabat, Morocco.
Zouaidia F; Department of pathology, Ibn Sina University Hospital Center, Rabat, Morocco.
Ibrahimi A; Medical Biotechnology Laboratory (MedBiotech), Rabat Medical & Pharmacy School, Mohammed Vth University in Rabat, Morocco.

J Biomol Struct Dyn ; 40(11): 5203-5210, 2022 07.

Article de En | MEDLINE | ID: mdl-33402049

Sujet(s)
Mots clés

Breast cancer; DNA binding domain; MD simulation; estrogen receptor α; virtual Screening

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du sein / Récepteur alpha des oestrogènes / Antinéoplasiques Type d'étude: Diagnostic_studies / Prognostic_studies Limites: Female / Humans Langue: En Journal: J Biomol Struct Dyn Année: 2022 Type de document: Article Pays d'affiliation: Maroc Pays de publication: Royaume-Uni

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