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Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response.
Golebski, Korneliusz; Layhadi, Janice A; Sahiner, Umit; Steveling-Klein, Esther H; Lenormand, Madison M; Li, Rachael C Y; Bal, Suzanne M; Heesters, Balthasar A; Vilà-Nadal, Gemma; Hunewald, Oliver; Montamat, Guillem; He, Feng Q; Ollert, Markus; Fedina, Oleksandra; Lao-Araya, Mongkol; Vijverberg, Susanne J H; Maitland-van der Zee, Anke-Hilse; van Drunen, Cornelis M; Fokkens, Wytske J; Durham, Stephen R; Spits, Hergen; Shamji, Mohamed H.
Affiliation
  • Golebski K; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Layhadi JA; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, UK; NIHR Biomedical Research Centre, Asthma UK Centre in Allergic Mechanisms of Asthma, London, Imperial College London, London, UK.
  • Sahiner U; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, UK.
  • Steveling-Klein EH; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, UK; Department of Dermatology, Allergy Unit, University Hospital Basel, Basel, Switzerland.
  • Lenormand MM; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, UK; NIHR Biomedical Research Centre, Asthma UK Centre in Allergic Mechanisms of Asthma, London, Imperial College London, London, UK.
  • Li RCY; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, UK; NIHR Biomedical Research Centre, Asthma UK Centre in Allergic Mechanisms of Asthma, London, Imperial College London, London, UK.
  • Bal SM; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Heesters BA; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Vilà-Nadal G; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, UK.
  • Hunewald O; Department of Infection and Immunity, Luxembourg Institute of Health (LIH), 29, rue Henri Koch, 4354 Esch-sur-Alzette, Luxembourg.
  • Montamat G; Department of Infection and Immunity, Luxembourg Institute of Health (LIH), 29, rue Henri Koch, 4354 Esch-sur-Alzette, Luxembourg; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
  • He FQ; Department of Infection and Immunity, Luxembourg Institute of Health (LIH), 29, rue Henri Koch, 4354 Esch-sur-Alzette, Luxembourg; Institute of Medical Microbiology, University Hospital Essen, University Duisburg-Essen, 45122 Essen, Germany.
  • Ollert M; Department of Infection and Immunity, Luxembourg Institute of Health (LIH), 29, rue Henri Koch, 4354 Esch-sur-Alzette, Luxembourg; Department of Dermatology and Allergy Center, Odense Research Centre for Anaphylaxis (ORCA), University of Southern Denmark, Odense, Denmark.
  • Fedina O; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, UK.
  • Lao-Araya M; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, UK.
  • Vijverberg SJH; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Maitland-van der Zee AH; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • van Drunen CM; Department of Otorhinolaryngology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Fokkens WJ; Department of Otorhinolaryngology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Durham SR; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, UK; NIHR Biomedical Research Centre, Asthma UK Centre in Allergic Mechanisms of Asthma, London, Imperial College London, London, UK.
  • Spits H; Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: hergen.spits@amsterdamumc.nl.
  • Shamji MH; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, Department of National Heart and Lung Institute, Imperial College London, London, UK; NIHR Biomedical Research Centre, Asthma UK Centre in Allergic Mechanisms of Asthma, London, Imperial College London, London, UK. Electronic add
Immunity ; 54(2): 291-307.e7, 2021 02 09.
Article de En | MEDLINE | ID: mdl-33450188

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lymphocytes / Rhinite allergique saisonnière / Interleukine-10 / Immunothérapie sublinguale Type d'étude: Clinical_trials / Risk_factors_studies Limites: Adult / Female / Humans / Male / Middle aged Langue: En Journal: Immunity Sujet du journal: ALERGIA E IMUNOLOGIA Année: 2021 Type de document: Article Pays d'affiliation: Pays-Bas Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lymphocytes / Rhinite allergique saisonnière / Interleukine-10 / Immunothérapie sublinguale Type d'étude: Clinical_trials / Risk_factors_studies Limites: Adult / Female / Humans / Male / Middle aged Langue: En Journal: Immunity Sujet du journal: ALERGIA E IMUNOLOGIA Année: 2021 Type de document: Article Pays d'affiliation: Pays-Bas Pays de publication: États-Unis d'Amérique