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TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies.
Akhmedov, Alexander; Crucet, Margot; Simic, Branko; Kraler, Simon; Bonetti, Nicole R; Ospelt, Caroline; Distler, Oliver; Ciurea, Adrian; Liberale, Luca; Jauhiainen, Matti; Metso, Jari; Miranda, Melroy; Cydecian, Rose; Schwarz, Lena; Fehr, Vera; Zilinyi, Rita; Amrollahi-Sharifabadi, Mohammad; Ntari, Lydia; Karagianni, Niki; Ruschitzka, Frank; Laaksonen, Reijo; Vanhoutte, Paul M; Kollias, George; Camici, Giovanni G; Lüscher, Thomas F.
Affiliation
  • Akhmedov A; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Crucet M; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Simic B; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Kraler S; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Bonetti NR; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Ospelt C; Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.
  • Distler O; Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.
  • Ciurea A; Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland.
  • Liberale L; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Jauhiainen M; Department of Internal Medicine and Medical Specialties, University of Genova, Genova, Italy.
  • Metso J; Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, Finland.
  • Miranda M; Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, Finland.
  • Cydecian R; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Schwarz L; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Fehr V; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Zilinyi R; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Amrollahi-Sharifabadi M; Department of Pharmacology, Faculty of Pharmacy, University of Debrecen, Debrecen, Hungary.
  • Ntari L; Center for Molecular Cardiology, Schlieren Campus, University of Zurich, 8001 Zurich, Switzerland.
  • Karagianni N; Institute for Immunology, Biomedical Sciences Research Center Alexander Fleming, Vari, Greece.
  • Ruschitzka F; Institute for Immunology, Biomedical Sciences Research Center Alexander Fleming, Vari, Greece.
  • Laaksonen R; Department of Cardiology, University Heart Center, University Hospital, Zürich, Switzerland.
  • Vanhoutte PM; Zora Biosciences Oy, Espoo, Finland.
  • Kollias G; Finnish Cardiovascular Research Center, University of Tampere and Finnish Clinical Biobank Tampere, Tampere University Hospital, Tampere, Finland.
  • Camici GG; Department of Pharmacology, Hong Kong University, Hong Kong, Peoples Republic of China.
  • Lüscher TF; Institute for Immunology, Biomedical Sciences Research Center Alexander Fleming, Vari, Greece.
Cardiovasc Res ; 118(1): 254-266, 2022 01 07.
Article de En | MEDLINE | ID: mdl-33483748
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Aorte thoracique / Arginase / Polyarthrite rhumatoïde / Vasodilatation / Endothélium vasculaire / Facteur de nécrose tumorale alpha / Cellules endothéliales / Récepteurs éboueurs de classe E / Inhibiteurs du facteur de nécrose tumorale Type d'étude: Observational_studies / Prognostic_studies / Risk_factors_studies Limites: Adult / Animals / Female / Humans / Male / Middle aged Langue: En Journal: Cardiovasc Res Année: 2022 Type de document: Article Pays d'affiliation: Suisse Pays de publication: Royaume-Uni
Texte intégral
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Aorte thoracique / Arginase / Polyarthrite rhumatoïde / Vasodilatation / Endothélium vasculaire / Facteur de nécrose tumorale alpha / Cellules endothéliales / Récepteurs éboueurs de classe E / Inhibiteurs du facteur de nécrose tumorale Type d'étude: Observational_studies / Prognostic_studies / Risk_factors_studies Limites: Adult / Animals / Female / Humans / Male / Middle aged Langue: En Journal: Cardiovasc Res Année: 2022 Type de document: Article Pays d'affiliation: Suisse Pays de publication: Royaume-Uni