Pathogenic mutations in the kinesin-3 motor KIF1A diminish force generation and movement through allosteric mechanisms.

Budaitis, Breane G; Jariwala, Shashank; Rao, Lu; Yue, Yang; Sept, David; Verhey, Kristen J; Gennerich, Arne

Budaitis, Breane G; Jariwala, Shashank; Rao, Lu; Yue, Yang; Sept, David; Verhey, Kristen J; Gennerich, Arne.

Affiliation

Budaitis BG; Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI.
Jariwala S; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI.
Rao L; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI.
Yue Y; Department of Anatomy and Structural Biology and Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, New York, NY.
Sept D; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI.
Verhey KJ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI.
Gennerich A; Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI.

J Cell Biol ; 220(4)2021 04 05.

Article de En | MEDLINE | ID: mdl-33496723

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Kinésine / Mutation faux-sens / Simulation de dynamique moléculaire Limites: Animals Langue: En Journal: J Cell Biol Année: 2021 Type de document: Article

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