Gastric cancer in Jammu and Kashmir, India: A review of genetic perspectives.
J Cancer Res Ther
; 18(4): 873-879, 2022.
Article
de En
| MEDLINE
| ID: mdl-33533734
ABSTRACT
Gastric Carcinoma (GC) is one of the most common malignancies, which accounts for 6.8% of total cancer population worldwide. In India, the northeastern region has the highest gastric cancer incidence, and the Kashmir Valley has a very high incidence of gastric cancer as compared to other parts of Northern India. It exceeds 40% of total cancers with an incidence rate of 3-6-fold higher than other metro cities of India. Gastric cancer is a heterogeneous disease where most of the cases are sporadic, and <15% are due to obvious familial clustering. The heterogeneous nature of the disease can be associated with differences in genetic makeup of an individual. A better understanding of genetic predisposition toward GC will be helpful in promoting personalized medicine. The aim of this review is to analyze the development and progression of GC and to explore the genetic perspectives of the disease with special emphasis on Jammu and Kashmir, India.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs de l'estomac
Type d'étude:
Incidence_studies
/
Prognostic_studies
Limites:
Humans
Pays/Région comme sujet:
Asia
Langue:
En
Journal:
J Cancer Res Ther
Sujet du journal:
NEOPLASIAS
/
TERAPEUTICA
Année:
2022
Type de document:
Article
Pays d'affiliation:
Inde