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A Burned-Out CD8+ T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy.
Sanmamed, Miguel F; Nie, Xinxin; Desai, Shruti S; Villaroel-Espindola, Franz; Badri, Ti; Zhao, Dejian; Kim, Anthony W; Ji, Lan; Zhang, Tianxiang; Quinlan, Edward; Cheng, Xiaoxiao; Han, Xue; Vesely, Matthew D; Nassar, Ala F; Sun, Jingwei; Zhang, Yu; Kim, Tae Kon; Wang, Jun; Melero, Ignacio; Herbst, Roy S; Schalper, Kurt A; Chen, Lieping.
Affiliation
  • Sanmamed MF; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Nie X; Division of Immunology and Immunotherapy, CIMA, Universidad de Navarra, Pamplona, Spain.
  • Desai SS; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Villaroel-Espindola F; Department of Pathology, Yale University, New Haven, Connecticut.
  • Badri T; Department of Pathology, Yale University, New Haven, Connecticut.
  • Zhao D; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Kim AW; Yale Center for Genome Analysis, Department of Genetics, Yale University, New Haven, Connecticut.
  • Ji L; Division of Thoracic Surgery, Yale University, New Haven, Connecticut.
  • Zhang T; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Quinlan E; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Cheng X; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Han X; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Vesely MD; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Nassar AF; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Sun J; Department of Dermatology, Yale University, New Haven, Connecticut.
  • Zhang Y; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Kim TK; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Wang J; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Melero I; Department of Medicine (Medical Oncology), Yale University, New Haven, Connecticut.
  • Herbst RS; Department of Medicine (Medical Oncology), Yale University, New Haven, Connecticut.
  • Schalper KA; Department of Immunobiology, Yale University, New Haven, Connecticut.
  • Chen L; Division of Immunology and Immunotherapy, CIMA, Universidad de Navarra, Pamplona, Spain.
Cancer Discov ; 11(7): 1700-1715, 2021 07.
Article de En | MEDLINE | ID: mdl-33658301

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Carcinome pulmonaire non à petites cellules / Lymphocytes T CD8/ / Microenvironnement tumoral / Tumeurs du poumon Type d'étude: Observational_studies / Risk_factors_studies Limites: Aged / Animals / Female / Humans / Male Langue: En Journal: Cancer Discov Année: 2021 Type de document: Article Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Carcinome pulmonaire non à petites cellules / Lymphocytes T CD8/ / Microenvironnement tumoral / Tumeurs du poumon Type d'étude: Observational_studies / Risk_factors_studies Limites: Aged / Animals / Female / Humans / Male Langue: En Journal: Cancer Discov Année: 2021 Type de document: Article Pays de publication: États-Unis d'Amérique