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Combination of ponatinib with deferoxamine synergistically mitigates ischemic heart injury via simultaneous prevention of necroptosis and ferroptosis.
Tu, Hua; Zhou, Yuan-Jing; Tang, Li-Jing; Xiong, Xiao-Ming; Zhang, Xiao-Jie; Ali Sheikh, Md Sayed; Zhang, Jie-Jie; Luo, Xiu-Ju; Yuan, Chuang; Peng, Jun.
Affiliation
  • Tu H; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China.
  • Zhou YJ; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China.
  • Tang LJ; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China; Department of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.
  • Xiong XM; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China; Hunan Provincial Key Laboratory of Cardiovascular Research, School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China.
  • Zhang XJ; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China.
  • Ali Sheikh MS; Internal Medicine Department, Cardiology, College of Medicine, Jouf University, Skaka, Aljouf, Saudi Arabia.
  • Zhang JJ; Department of Obstetrics, Xiangya Hospital Central South University, Changsha, China; Hunan Engineering Research Center of Early Life Development and Disease Prevention, Changsha, China.
  • Luo XJ; Department of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.
  • Yuan C; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China. Electronic address: aeolus.yc@csu.edu.cn.
  • Peng J; Department of Pharmacology, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China; Hunan Provincial Key Laboratory of Cardiovascular Research, School of Pharmaceutical Sciences, Central South University, Changsha, 410078, China. Electronic address: junpeng@csu.
Eur J Pharmacol ; 898: 173999, 2021 May 05.
Article de En | MEDLINE | ID: mdl-33675785
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pyridazines / Lésion de reperfusion myocardique / Myocytes cardiaques / Déferoxamine / Ferroptose / Nécroptose / Imidazoles / Infarctus du myocarde Limites: Animals Langue: En Journal: Eur J Pharmacol Année: 2021 Type de document: Article Pays d'affiliation: Chine Pays de publication: Pays-Bas
Texte intégral
Ajouter à My VHL
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XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pyridazines / Lésion de reperfusion myocardique / Myocytes cardiaques / Déferoxamine / Ferroptose / Nécroptose / Imidazoles / Infarctus du myocarde Limites: Animals Langue: En Journal: Eur J Pharmacol Année: 2021 Type de document: Article Pays d'affiliation: Chine Pays de publication: Pays-Bas