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Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color.
Simcoe, Mark; Valdes, Ana; Liu, Fan; Furlotte, Nicholas A; Evans, David M; Hemani, Gibran; Ring, Susan M; Smith, George Davey; Duffy, David L; Zhu, Gu; Gordon, Scott D; Medland, Sarah E; Vuckovic, Dragana; Girotto, Giorgia; Sala, Cinzia; Catamo, Eulalia; Concas, Maria Pina; Brumat, Marco; Gasparini, Paolo; Toniolo, Daniela; Cocca, Massimiliano; Robino, Antonietta; Yazar, Seyhan; Hewitt, Alex; Wu, Wenting; Kraft, Peter; Hammond, Christopher J; Shi, Yuan; Chen, Yan; Zeng, Changqing; Klaver, Caroline C W; Uitterlinden, Andre G; Ikram, M Arfan; Hamer, Merel A; van Duijn, Cornelia M; Nijsten, Tamar; Han, Jiali; Mackey, David A; Martin, Nicholas G; Cheng, Ching-Yu; Hinds, David A; Spector, Timothy D; Kayser, Manfred; Hysi, Pirro G.
Affiliation
  • Simcoe M; Department of Twins Research and Genetic Epidemiology, King's College London, London, UK.
  • Valdes A; Department of Ophthalmology, King's College London, London, UK.
  • Liu F; Department of Twins Research and Genetic Epidemiology, King's College London, London, UK.
  • Furlotte NA; Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK.
  • Evans DM; Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.
  • Hemani G; Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
  • Ring SM; University of Chinese Academy of Sciences, Beijing, China.
  • Smith GD; 23andMe Inc., Sunnyvale, CA, USA.
  • Duffy DL; University of Queensland Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.
  • Zhu G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Gordon SD; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Medland SE; Population Health Sciences Bristol Medical School University of Bristol, Bristol, UK.
  • Vuckovic D; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Girotto G; Population Health Sciences Bristol Medical School University of Bristol, Bristol, UK.
  • Sala C; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Catamo E; Population Health Sciences Bristol Medical School University of Bristol, Bristol, UK.
  • Concas MP; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Brumat M; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Gasparini P; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Toniolo D; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Cocca M; Department of Medical Sciences, University of Trieste, Trieste, Italy.
  • Robino A; Institute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
  • Yazar S; Epidemiology and Biostatistics Department, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.
  • Hewitt A; Department of Medical Sciences, University of Trieste, Trieste, Italy.
  • Wu W; Institute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
  • Kraft P; Division of Genetics of Common Disorders, S. Raffaele Scientific Institute, Milan, Italy.
  • Hammond CJ; Department of Medical Sciences, University of Trieste, Trieste, Italy.
  • Shi Y; Institute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
  • Chen Y; Department of Medical Sciences, University of Trieste, Trieste, Italy.
  • Zeng C; Department of Medical Sciences, University of Trieste, Trieste, Italy.
  • Klaver CCW; Institute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
  • Uitterlinden AG; Division of Genetics of Common Disorders, S. Raffaele Scientific Institute, Milan, Italy.
  • Ikram MA; Institute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
  • Hamer MA; Institute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
  • van Duijn CM; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Australia.
  • Nijsten T; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Australia.
  • Han J; Centre for Eye Research Australia, University of Melbourne, Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
  • Mackey DA; School of Medicine, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia.
  • Martin NG; Department of Epidemiology, Fairbanks School of Public Health, Indiana University, and Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA.
  • Cheng CY; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
  • Hinds DA; Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Spector TD; Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.
  • Kayser M; Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
  • Hysi PG; University of Chinese Academy of Sciences, Beijing, China.
Sci Adv ; 7(11)2021 03.
Article de En | MEDLINE | ID: mdl-33692100
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Type d'étude: Prognostic_studies / Risk_factors_studies Langue: En Journal: Sci Adv Année: 2021 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Type d'étude: Prognostic_studies / Risk_factors_studies Langue: En Journal: Sci Adv Année: 2021 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: États-Unis d'Amérique