Magnetic cobalt oxide nanosheets: green synthesis and in vitro cytotoxicity.
Bioprocess Biosyst Eng
; 44(7): 1423-1432, 2021 Jul.
Article
de En
| MEDLINE
| ID: mdl-33709297
ABSTRACT
Cobalt oxide nanoparticles were prepared via green chemistry route and fully characterized by Field Emission Scanning Electron Microscope (FESEM), Energy-dispersive X-ray spectroscopy (EDAX), X-ray diffraction (XRD), High-resolution transmission electron microscopy (HRTEM) and Transmission electron microscopy (TEM) analyses; the CoO and Co3O4 nanoparticles, in sheet-shaped cobalt oxide form, ensued simultaneously in one step. The varying concentrations of NPs were analyzed via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test on the cancer cell line (U87) which revealed that with increasing concentration of cobalt oxide nanoparticles, the survival rate of U87 tumor cells decreases; IC50 of nanoparticles being ~ 55 µg/ml-1.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Oxydes
/
Cobalt
/
Nanotechnologie
/
Nanoparticules métalliques
/
Technologie de la chimie verte
Limites:
Humans
Langue:
En
Journal:
Bioprocess Biosyst Eng
Sujet du journal:
BIOTECNOLOGIA
/
ENGENHARIA BIOMEDICA
Année:
2021
Type de document:
Article
Pays d'affiliation:
Iran