Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A<sub>1</sub> Receptor in Living Cells.

Comeo, Eleonora; Trinh, Phuc; Nguyen, Anh T; Nowell, Cameron J; Kindon, Nicholas D; Soave, Mark; Stoddart, Leigh A; White, Jonathan M; Hill, Stephen J; Kellam, Barrie; Halls, Michelle L; May, Lauren T; Scammells, Peter J

Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A₁ Receptor in Living Cells.

Comeo, Eleonora; Trinh, Phuc; Nguyen, Anh T; Nowell, Cameron J; Kindon, Nicholas D; Soave, Mark; Stoddart, Leigh A; White, Jonathan M; Hill, Stephen J; Kellam, Barrie; Halls, Michelle L; May, Lauren T; Scammells, Peter J.

Affiliation

Comeo E; Medicinal Chemistry, Monash University, Parkville, Victoria 3052, Australia.
Trinh P; Division of Biomolecular Sciences and Medicinal Chemistry, School of Pharmacy, Biodiscovery Institute, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
Nguyen AT; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, B15 2TT and University of Nottingham, Birmingham NG7 2UH, United Kingdom.
Nowell CJ; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
Kindon ND; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
Soave M; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
Stoddart LA; Division of Biomolecular Sciences and Medicinal Chemistry, School of Pharmacy, Biodiscovery Institute, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
White JM; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, B15 2TT and University of Nottingham, Birmingham NG7 2UH, United Kingdom.
Hill SJ; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham NG7 2UH, United Kingdom.
Kellam B; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, B15 2TT and University of Nottingham, Birmingham NG7 2UH, United Kingdom.
Halls ML; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queens Medical Centre, University of Nottingham, Nottingham NG7 2UH, United Kingdom.
May LT; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham, B15 2TT and University of Nottingham, Birmingham NG7 2UH, United Kingdom.
Scammells PJ; School of Chemistry and the Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, Victoria 3010, Australia.

J Med Chem ; 64(10): 6670-6695, 2021 05 27.

Article de En | MEDLINE | ID: mdl-33724031

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteur A1 à l'adénosine / Antagonistes du récepteur A1 à l'adénosine / Colorants fluorescents Limites: Humans Langue: En Journal: J Med Chem Sujet du journal: QUIMICA Année: 2021 Type de document: Article Pays d'affiliation: Australie

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