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Chaiqin chengqi decoction ameliorates acute pancreatitis in mice via inhibition of neuron activation-mediated acinar cell SP/NK1R signaling pathways.
Han, Chenxia; Du, Dan; Wen, Yongjian; Li, Jiawang; Wang, Rui; Jin, Tao; Yang, Jingyu; Shi, Na; Jiang, Kun; Deng, Lihui; Fu, Xianghui; Mukherjee, Rajarshi; Windsor, John A; Hong, Jiwon; Phillips, Anthony R; Sutton, Robert; Huang, Wei; Liu, Tingting; Xia, Qing.
Affiliation
  • Han C; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Du D; West China-Washington Mitochondria and Metabolism Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Wen Y; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Li J; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Wang R; Core Research Facilities, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Jin T; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Yang J; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Shi N; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Jiang K; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Deng L; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Fu X; Division of Endocrinology and Metabolism, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China.
  • Mukherjee R; Liverpool Pancreatitis Study Group, Royal Liverpool University Hospital and Institute of Translational Medicine, University of Liverpool, Liverpool, L69 3GE, United Kingdom.
  • Windsor JA; Surgical and Translational Research Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, 1023, New Zealand.
  • Hong J; Surgical and Translational Research Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, 1023, New Zealand; Applied Surgery and Metabolism Laboratory, School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.
  • Phillips AR; Surgical and Translational Research Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, 1023, New Zealand; Applied Surgery and Metabolism Laboratory, School of Biological Sciences, University of Auckland, Auckland, 1010, New Zealand.
  • Sutton R; Liverpool Pancreatitis Study Group, Royal Liverpool University Hospital and Institute of Translational Medicine, University of Liverpool, Liverpool, L69 3GE, United Kingdom.
  • Huang W; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Liu T; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address: tingting_liu66@163.com.
  • Xia Q; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address: xiaqing@medmail.com.cn.
J Ethnopharmacol ; 274: 114029, 2021 Jun 28.
Article de En | MEDLINE | ID: mdl-33731310
Sujet(s)
Analgésiques/usage thérapeutique; Anti-inflammatoires/usage thérapeutique; Médicaments issus de plantes chinoises/usage thérapeutique; Douleur/traitement médicamenteux; Pancréatite/traitement médicamenteux; Récepteur de la neurokinine 1/métabolisme; Substance P/métabolisme; Cellules acineuses/effets des médicaments et des substances chimiques; Cellules acineuses/métabolisme; Analgésiques/pharmacologie; Animaux; Anti-inflammatoires/pharmacologie; Dérivés du biphényle/analyse; Dérivés du biphényle/pharmacologie; Dérivés du biphényle/usage thérapeutique; Céruléine; Médicaments issus de plantes chinoises/composition chimique; Médicaments issus de plantes chinoises/pharmacologie; Émodine/analyse; Émodine/pharmacologie; Émodine/usage thérapeutique; Flavonoïdes/analyse; Flavonoïdes/pharmacologie; Flavonoïdes/usage thérapeutique; Ganglions sensitifs des nerfs spinaux/effets des médicaments et des substances chimiques; Ganglions sensitifs des nerfs spinaux/métabolisme; Humains; Lignanes/analyse; Lignanes/pharmacologie; Lignanes/usage thérapeutique; Mâle; Souris de lignée C57BL; Neurones/effets des médicaments et des substances chimiques; Neurones/métabolisme; Douleur/métabolisme; Douleur/anatomopathologie; Pancréas/effets des médicaments et des substances chimiques; Pancréas/métabolisme; Pancréas/anatomopathologie; Pancréatite/induit chimiquement; Pancréatite/métabolisme; Pancréatite/anatomopathologie; Récepteur de la neurokinine 1/génétique; Transduction du signal/effets des médicaments et des substances chimiques; Moelle spinale/effets des médicaments et des substances chimiques; Moelle spinale/métabolisme; Substance P/génétique
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Douleur / Pancréatite / Médicaments issus de plantes chinoises / Substance P / Récepteur de la neurokinine 1 / Analgésiques / Anti-inflammatoires Type d'étude: Prognostic_studies Langue: En Journal: J Ethnopharmacol Année: 2021 Type de document: Article Pays d'affiliation: Chine Pays de publication: Irlande
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Douleur / Pancréatite / Médicaments issus de plantes chinoises / Substance P / Récepteur de la neurokinine 1 / Analgésiques / Anti-inflammatoires Type d'étude: Prognostic_studies Langue: En Journal: J Ethnopharmacol Année: 2021 Type de document: Article Pays d'affiliation: Chine Pays de publication: Irlande