Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer.

Zhang, Baotong; Li, Yixiang; Wu, Qiao; Xie, Lin; Barwick, Benjamin; Fu, Changying; Li, Xin; Wu, Daqing; Xia, Siyuan; Chen, Jing; Qian, Wei Ping; Yang, Lily; Osunkoya, Adeboye O; Boise, Lawrence; Vertino, Paula M; Zhao, Yichao; Li, Menglin; Chen, Hsiao-Rong; Kowalski, Jeanne; Kucuk, Omer; Zhou, Wei; Dong, Jin-Tang

Zhang, Baotong; Li, Yixiang; Wu, Qiao; Xie, Lin; Barwick, Benjamin; Fu, Changying; Li, Xin; Wu, Daqing; Xia, Siyuan; Chen, Jing; Qian, Wei Ping; Yang, Lily; Osunkoya, Adeboye O; Boise, Lawrence; Vertino, Paula M; Zhao, Yichao; Li, Menglin; Chen, Hsiao-Rong; Kowalski, Jeanne; Kucuk, Omer; Zhou, Wei; Dong, Jin-Tang.

Affiliation

Zhang B; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.
Li Y; Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Wu Q; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.
Xie L; Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Barwick B; Department of Genetics and Cell Biology, Nankai University College of Life Sciences, Tianjin, China.
Fu C; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.
Li X; Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Wu D; Third Affiliated Hospital of Kunming Medical University, Cancer Hospital of Yunnan Province, Kunming, China.
Xia S; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.
Chen J; Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Qian WP; Department of Genetics and Cell Biology, Nankai University College of Life Sciences, Tianjin, China.
Yang L; Department of Human Cell Biology and Genetics, Southern University of Science and Technology School of Medicine, Shenzhen, China.
Osunkoya AO; Molecular Oncology and Biomarkers Program, Georgia Cancer Center, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Boise L; Molecular Oncology and Biomarkers Program, Georgia Cancer Center, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Vertino PM; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.
Zhao Y; Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Li M; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.
Chen HR; Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Kowalski J; Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Kucuk O; Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA.
Zhou W; Winship Cancer Institute, Emory University, Atlanta, GA, USA.
Dong JT; Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA.

Nat Commun ; 12(1): 1714, 2021 03 17.

Article de En | MEDLINE | ID: mdl-33731701

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs osseuses / Facteurs de transcription Krüppel-like / Transition épithélio-mésenchymateuse / Tumeurs prostatiques résistantes à la castration / Carcinogenèse Limites: Animals / Humans / Male Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2021 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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