Decoy Receptor 3 Inhibits Monosodium Urate-Induced NLRP3 Inflammasome Activation <i>via</i> Reduction of Reactive Oxygen Species Production and Lysosomal Rupture.

Pan, Yi-Gen; Huang, Ming-Ting; Sekar, Ponarulselvam; Huang, Duen-Yi; Lin, Wan-Wan; Hsieh, Shie-Liang

Decoy Receptor 3 Inhibits Monosodium Urate-Induced NLRP3 Inflammasome Activation via Reduction of Reactive Oxygen Species Production and Lysosomal Rupture.

Pan, Yi-Gen; Huang, Ming-Ting; Sekar, Ponarulselvam; Huang, Duen-Yi; Lin, Wan-Wan; Hsieh, Shie-Liang.

Affiliation

Pan YG; Institute of Immunology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Huang MT; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Sekar P; Genomics Research Center, Academia Sinica, Taipei, Taiwan.
Huang DY; Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lin WW; Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan.
Hsieh SL; Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Front Immunol ; 12: 638676, 2021.

Article de En | MEDLINE | ID: mdl-33746978

Sujet(s)
Mots clés

NLRP3 inflammasome; cathepsin; decoy receptor 3; gout; lysosome; monosodium urate; reactive oxygen species

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Membre-6b de la superfamille des récepteurs au TNF / Inflammasomes / Goutte / Lysosomes / Macrophages / Granulocytes neutrophiles Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Front Immunol Année: 2021 Type de document: Article Pays d'affiliation: Taïwan

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