Clinical findings in patients with SLE whose sera contain antibodies to ribosomal ribonucleoprotein.
Immunol Lett
; 18(1): 1-3, 1988 May.
Article
de En
| MEDLINE
| ID: mdl-3378827
ABSTRACT
In a clinical and serological study performed on a large series of patients with different connective tissue diseases, anti-ribosomal ribonucleoprotein (rRNP) antibodies were detected only in a small proportion of sera with systemic lupus erythematosus (SLE). SLE patients positive for anti-rRNP autoantibodies showed a significantly higher incidence of hemolytic anemia. The reasons for this surprising association are still unclear; however, this finding suggests that rRNP precipitin might be considered as a useful marker of a particular subgroup of patients with SLE.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Ribonucléoprotéines
/
Ribosomes
/
Autoanticorps
/
Lupus érythémateux disséminé
Type d'étude:
Diagnostic_studies
/
Etiology_studies
Limites:
Humans
Langue:
En
Journal:
Immunol Lett
Année:
1988
Type de document:
Article
Pays d'affiliation:
Italie