Russell Body Typhlitis: A Case Report and Literature Review.
Int J Surg Pathol
; 29(8): 877-881, 2021 Dec.
Article
de En
| MEDLINE
| ID: mdl-33829929
ABSTRACT
Russell bodies are accumulation of immunoglobulin in plasma cells forming intracytoplasmic inclusions. Russell body colitis is rare with only 3 cases described in the English literature up to date. We report a 78-year-old male with cirrhosis showing prominent cecal infiltration of Russell body containing plasma cells. Plasma cells showed no nuclear atypia or mitoses, and no evidence of light chain restriction. In this article, we report a fourth case of Russell body colitis, that is unique in being localized to the cecum in contrast to the other 3, 1 of which was in an inflammatory polyp in the sigmoid colon, 1 in a rectal tubulovillous adenoma and 1 as part of diffuse gastrointestinal disease. This is therefore the first report of localized Russell body typhlitis, occurring in a cirrhotic patient in whom an adjacent erosion was likely nonsteroidal anti-inflammatory drug-associated, a combination that may have facilitated the formation of Russell bodies.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Plasmocytes
/
Caecum
/
Corps d'inclusion
/
Typhlite
/
Muqueuse intestinale
Type d'étude:
Systematic_reviews
Limites:
Aged
/
Humans
/
Male
Langue:
En
Journal:
Int J Surg Pathol
Sujet du journal:
PATOLOGIA
Année:
2021
Type de document:
Article
Pays d'affiliation:
Canada