Primary Testicular Neuroendocrine Tumor Coexisting With Seminoma Sharing Germ Cell Origin.
Int J Surg Pathol
; 29(8): 887-891, 2021 Dec.
Article
de En
| MEDLINE
| ID: mdl-33847540
ABSTRACT
A 40-year-old, male, Japanese patient presented with the complaint of painless, right testicular swelling. Tumor markers for testicular cancer were normal. He underwent radical orchiectomy with the clinical diagnosis of stage I seminoma. Pathological examination revealed seminoma and coexisting neuroendocrine tumor (NET). Germ cell neoplasia in situ (GCNIS) was present in the vicinity of seminoma, but there was no continuity between NET and seminoma. Tumor cells of both lesions displayed amplification of 12p and isochromosome 12p on fluorescence in situ hybridization, suggesting that both tumors originated from GCNIS. The present report is the first to describe a case of primary testicular NET coexisting with seminoma in an ipsilateral testis.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs du testicule
/
Testicule
/
Séminome
/
Tumeurs neuroendocrines
/
Tumeurs primitives multiples
Limites:
Adult
/
Humans
/
Male
Langue:
En
Journal:
Int J Surg Pathol
Sujet du journal:
PATOLOGIA
Année:
2021
Type de document:
Article
Pays d'affiliation:
Japon