Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis.

Garnish, Sarah E; Meng, Yanxiang; Koide, Akiko; Sandow, Jarrod J; Denbaum, Eric; Jacobsen, Annette V; Yeung, Wayland; Samson, Andre L; Horne, Christopher R; Fitzgibbon, Cheree; Young, Samuel N; Smith, Phoebe P C; Webb, Andrew I; Petrie, Emma J; Hildebrand, Joanne M; Kannan, Natarajan; Czabotar, Peter E; Koide, Shohei; Murphy, James M

Garnish, Sarah E; Meng, Yanxiang; Koide, Akiko; Sandow, Jarrod J; Denbaum, Eric; Jacobsen, Annette V; Yeung, Wayland; Samson, Andre L; Horne, Christopher R; Fitzgibbon, Cheree; Young, Samuel N; Smith, Phoebe P C; Webb, Andrew I; Petrie, Emma J; Hildebrand, Joanne M; Kannan, Natarajan; Czabotar, Peter E; Koide, Shohei; Murphy, James M.

Affiliation

Garnish SE; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Meng Y; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Koide A; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Sandow JJ; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Denbaum E; Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA.
Jacobsen AV; Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA.
Yeung W; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Samson AL; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Horne CR; Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA.
Fitzgibbon C; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Young SN; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Smith PPC; Institute of Bioinformatics, University of Georgia, Athens, GA, USA.
Webb AI; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Petrie EJ; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Hildebrand JM; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Kannan N; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
Czabotar PE; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Koide S; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Murphy JM; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

Nat Commun ; 12(1): 2211, 2021 04 13.

Article de En | MEDLINE | ID: mdl-33850121

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protein kinases / Mort cellulaire / Receptor-Interacting Protein Serine-Threonine Kinases / Nécroptose Limites: Animals / Humans Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2021 Type de document: Article Pays d'affiliation: Australie

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