Identification of Crocin as a New hIAPP Amyloid Inhibitor via a Simple Yet Highly Biospecific Screening System.

Lu, Jingxuan; Lu, Zhongxia; Liu, Luxin; Li, Xinyu; Yu, Wengong; Lu, Xinzhi

Lu, Jingxuan; Lu, Zhongxia; Liu, Luxin; Li, Xinyu; Yu, Wengong; Lu, Xinzhi.

Affiliation

Lu J; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, P. R. China.
Lu Z; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, P. R. China.
Liu L; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, P. R. China.
Li X; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, P. R. China.
Yu W; Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, P. R. China.
Lu X; Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266003, P. R. China.

Chem Biodivers ; 18(6): e2100270, 2021 Jun.

Article de En | MEDLINE | ID: mdl-33890414

Sujet(s)
Mots clés

T2D; amyloid formation.; hIAPP; saccharomyces cerevisiae; screening system

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Caroténoïdes / Diabète de type 2 / Polypeptide amyloïde des ilots / Agrégation pathologique de protéines / Hypoglycémiants Type d'étude: Diagnostic_studies / Screening_studies Limites: Humans Langue: En Journal: Chem Biodivers Sujet du journal: BIOQUIMICA / QUIMICA Année: 2021 Type de document: Article Pays de publication: Suisse

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