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A pain killer without analgesic tolerance designed by co-targeting PSD-95-nNOS interaction and α2-containning GABAARs.
Li, Jun; Zhang, Lin; Xu, Chu; Shen, Ying-Ying; Lin, Yu-Hui; Zhang, Yu; Wu, Hai-Yin; Chang, Lei; Zhang, Ying-Dong; Chen, Rong; Zhang, Zheng-Ping; Luo, Chun-Xia; Li, Fei; Zhu, Dong-Ya.
Affiliation
  • Li J; Department of Pharmacology, School of Pharmacy, Nanjing Medical University, China.
  • Zhang L; Department of Pharmacy, Nanjing First Hospital, Nanjing Medical University, China.
  • Xu C; Department of Pharmacology, School of Pharmacy, Nanjing Medical University, China.
  • Shen YY; Department of Pharmacology, School of Pharmacy, Nanjing Medical University, China.
  • Lin YH; Department of Pharmacology, School of Pharmacy, Nanjing Medical University, China.
  • Zhang Y; Department of Pharmacology, School of Pharmacy, Nanjing Medical University, China.
  • Wu HY; Department of Pharmacology, School of Pharmacy, Nanjing Medical University, China.
  • Chang L; Department of Pharmacology, School of Pharmacy, Nanjing Medical University, China.
  • Zhang YD; Department of Pharmacology, School of Pharmacy, Nanjing Medical University, China.
  • Chen R; Department of Neurology, Nanjing First Hospital, Nanjing Medical University, China.
  • Zhang ZP; Center of Drug Metabolism & Pharmacokinetics, Yantai YenePharma Co., Ltd, China.
  • Luo CX; Center of Drug Metabolism & Pharmacokinetics, Yantai YenePharma Co., Ltd, China.
  • Li F; Department of Pharmacology, School of Pharmacy, Nanjing Medical University, China.
  • Zhu DY; Department of Medicinal Chemistry, School of Pharmacy, Nanjing Medical University, China.
Theranostics ; 11(12): 5970-5985, 2021.
Article de En | MEDLINE | ID: mdl-33897893

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteurs GABA-A / Nitric oxide synthase type I / Homologue-4 de la protéine Disks Large / Analgésiques / Névralgie Limites: Animals / Humans / Male Langue: En Journal: Theranostics Année: 2021 Type de document: Article Pays d'affiliation: Chine Pays de publication: Australie

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteurs GABA-A / Nitric oxide synthase type I / Homologue-4 de la protéine Disks Large / Analgésiques / Névralgie Limites: Animals / Humans / Male Langue: En Journal: Theranostics Année: 2021 Type de document: Article Pays d'affiliation: Chine Pays de publication: Australie