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Xanthohumol ameliorates memory impairment and reduces the deposition of ß-amyloid in APP/PS1 mice via regulating the mTOR/LC3II and Bax/Bcl-2 signalling pathways.
Sun, Xiao-Lei; Zhang, Jia-Bao; Guo, Yun-Xiang; Xia, Tian-Shuang; Xu, Ling-Chuan; Rahmand, Khalid; Wang, Guo-Ping; Li, Xiao-Jin; Han, Ting; Wang, Na-Ni; Xin, Hai-Liang.
Affiliation
  • Sun XL; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, ShanghaiChina.
  • Zhang JB; School of Pharmacy, Shandong University of Traditional Chinese Medicine, JinanChina.
  • Guo YX; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, ShanghaiChina.
  • Xia TS; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, ShanghaiChina.
  • Xu LC; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, ShanghaiChina.
  • Rahmand K; School of Pharmacy, Shandong University of Traditional Chinese Medicine, JinanChina.
  • Wang GP; Faculty of Science, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.
  • Li XJ; Xinjiang Institute of Chinese Materia Medica, Urumqi, China.
  • Han T; Xinjiang Institute of Chinese Materia Medica, Urumqi, China.
  • Wang NN; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, ShanghaiChina.
  • Xin HL; Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, ShanghaiChina.
J Pharm Pharmacol ; 73(9): 1230-1239, 2021 Aug 12.
Article de En | MEDLINE | ID: mdl-33909081

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Propiophénones / Flavonoïdes / Peptides bêta-amyloïdes / Humulus / Protéine Bax / Sérine-thréonine kinases TOR / Hippocampe / Troubles de la mémoire Limites: Animals Langue: En Journal: J Pharm Pharmacol Année: 2021 Type de document: Article Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Propiophénones / Flavonoïdes / Peptides bêta-amyloïdes / Humulus / Protéine Bax / Sérine-thréonine kinases TOR / Hippocampe / Troubles de la mémoire Limites: Animals Langue: En Journal: J Pharm Pharmacol Année: 2021 Type de document: Article Pays de publication: Royaume-Uni