Examination of the antiepileptic effects of valacyclovir using kindling mice- search for novel antiepileptic agents by drug repositioning using a large medical information database.

Takahashi, Shimon; Takechi, Kenshi; Jozukuri, Natsumi; Niimura, Takahiro; Chuma, Masayuki; Goda, Mitsuhiro; Zamami, Yoshito; Izawa-Ishizawa, Yuki; Imanishi, Masaki; Horinouchi, Yuya; Ikeda, Yasumasa; Tsuchiya, Koichiro; Yanagawa, Hiroaki; Ishizawa, Keisuke

Takahashi, Shimon; Takechi, Kenshi; Jozukuri, Natsumi; Niimura, Takahiro; Chuma, Masayuki; Goda, Mitsuhiro; Zamami, Yoshito; Izawa-Ishizawa, Yuki; Imanishi, Masaki; Horinouchi, Yuya; Ikeda, Yasumasa; Tsuchiya, Koichiro; Yanagawa, Hiroaki; Ishizawa, Keisuke.

Affiliation

Takahashi S; Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Japan; Department of Pharmacy, Tokushima University Hospital, Japan.
Takechi K; Department of Drug Information Analysis, College of Pharmaceutical Sciences, Matsuyama University, Japan. Electronic address: dph20010@s.okadai.jp.
Jozukuri N; Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Japan.
Niimura T; Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Japan.
Chuma M; Department of Hospital Pharmacy & Pharmacology, Asahikawa Medical University & University Hospital, Japan.
Goda M; Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Japan; Clinical Research Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima, Japan.
Zamami Y; Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Japan; Department of Pharmacy, Tokushima University Hospital, Japan.
Izawa-Ishizawa Y; Department of Pharmacology, Institute of Biomedical Sciences, Tokushima University Graduate School, AWA Support Center, Japan.
Imanishi M; Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Japan.
Horinouchi Y; Department of Pharmaceutical Care and Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihamabouji Yamashiro-cho, Tokushima, 770-8514, Japan.
Ikeda Y; Department of Pharmacology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Tsuchiya K; Department of Medical Pharmacology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Yanagawa H; Clinical Research Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima, Japan.
Ishizawa K; Department of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Japan; Department of Pharmacy, Tokushima University Hospital, Japan.

Eur J Pharmacol ; 902: 174099, 2021 Jul 05.

Article de En | MEDLINE | ID: mdl-33910036

Sujet(s)
Mots clés

Drug repositioning; Epilepsy; Large medical information database; Valacyclovir

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Crises épileptiques / Valaciclovir / Embrasement / Anticonvulsivants Type d'étude: Prognostic_studies Limites: Animals / Humans / Male Langue: En Journal: Eur J Pharmacol Année: 2021 Type de document: Article Pays d'affiliation: Japon Pays de publication: Pays-Bas

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