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Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neurons.
Kim, Sun-Gyun; Lee, Suho; Kim, Yangsik; Park, Jieun; Woo, Doyeon; Kim, Dayeon; Li, Yan; Shin, Wangyong; Kang, Hyunjeong; Yook, Chaehyun; Lee, Minji; Kim, Kyungdeok; Roh, Junyeop Daniel; Ryu, Jeseung; Jung, Hwajin; Um, Seung Min; Yang, Esther; Kim, Hyun; Han, Jinju; Heo, Won Do; Kim, Eunjoon.
Affiliation
  • Kim SG; Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS), Daejeon, Korea.
  • Lee S; Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS), Daejeon, Korea.
  • Kim Y; Graduate School of Medical Science and Engineering, Korea Advanced Institute for Science and Technology (KAIST), Daejeon, Korea.
  • Park J; Department of Biological Sciences, KAIST, Daejeon, Korea.
  • Woo D; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Korea.
  • Kim D; Graduate School of Medical Science and Engineering, Korea Advanced Institute for Science and Technology (KAIST), Daejeon, Korea.
  • Li Y; Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS), Daejeon, Korea.
  • Shin W; Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS), Daejeon, Korea.
  • Kang H; Department of Biological Sciences, KAIST, Daejeon, Korea.
  • Yook C; Department of Biological Sciences, KAIST, Daejeon, Korea.
  • Lee M; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Korea.
  • Kim K; Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS), Daejeon, Korea.
  • Roh JD; Department of Biological Sciences, KAIST, Daejeon, Korea.
  • Ryu J; Department of Biological Sciences, KAIST, Daejeon, Korea.
  • Jung H; Center for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS), Daejeon, Korea.
  • Um SM; Department of Biological Sciences, KAIST, Daejeon, Korea.
  • Yang E; Department of Anatomy and Division of Brain Korea 21, Biomedical Science, College of Medicine, Korea University, Seoul, Korea.
  • Kim H; Department of Anatomy and Division of Brain Korea 21, Biomedical Science, College of Medicine, Korea University, Seoul, Korea.
  • Han J; Graduate School of Medical Science and Engineering, Korea Advanced Institute for Science and Technology (KAIST), Daejeon, Korea.
  • Heo WD; Department of Biological Sciences, KAIST, Daejeon, Korea.
  • Kim E; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Korea.
Nat Commun ; 12(1): 2695, 2021 05 11.
Article de En | MEDLINE | ID: mdl-33976205

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Encéphale / Protéines / Sérine-thréonine kinases TOR / Complexe-1 cible mécanistique de la rapamycine / Complexe-2 cible mécanistique de la rapamycine / Neurones Limites: Animals / Humans Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2021 Type de document: Article

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Encéphale / Protéines / Sérine-thréonine kinases TOR / Complexe-1 cible mécanistique de la rapamycine / Complexe-2 cible mécanistique de la rapamycine / Neurones Limites: Animals / Humans Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2021 Type de document: Article