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α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein pathology.
Stykel, Morgan G; Humphries, Kayla M; Kamski-Hennekam, Evelyn; Buchner-Duby, Brodie; Porte-Trachsel, Natalie; Ryan, Tammy; Coackley, Carla L; Bamm, Vladimir V; Harauz, George; Ryan, Scott D.
Affiliation
  • Stykel MG; Department of Molecular and Cellular Biology, The University of Guelph, Guelph, ON N1G 2W1, Canada.
  • Humphries KM; Department of Molecular and Cellular Biology, The University of Guelph, Guelph, ON N1G 2W1, Canada.
  • Kamski-Hennekam E; Department of Molecular and Cellular Biology, The University of Guelph, Guelph, ON N1G 2W1, Canada.
  • Buchner-Duby B; Department of Molecular and Cellular Biology, The University of Guelph, Guelph, ON N1G 2W1, Canada.
  • Porte-Trachsel N; Department of Molecular and Cellular Biology, The University of Guelph, Guelph, ON N1G 2W1, Canada.
  • Ryan T; Department of Molecular and Cellular Biology, The University of Guelph, Guelph, ON N1G 2W1, Canada.
  • Coackley CL; Department of Molecular and Cellular Biology, The University of Guelph, Guelph, ON N1G 2W1, Canada.
  • Bamm VV; Department of Molecular and Cellular Biology, The University of Guelph, Guelph, ON N1G 2W1, Canada.
  • Harauz G; Department of Molecular and Cellular Biology, The University of Guelph, Guelph, ON N1G 2W1, Canada.
  • Ryan SD; Department of Molecular and Cellular Biology, The University of Guelph, Guelph, ON N1G 2W1, Canada; Neurodegenerative Disease Center, Scintillon Institute, 6868 Nancy Ridge Drive, San Diego, CA 92121, USA. Electronic address: sryan03@uoguelph.ca.
Cell Rep ; 35(6): 109099, 2021 05 11.
Article de En | MEDLINE | ID: mdl-33979611
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Maladie de Parkinson / Alpha-Synucléine / Exocytose / Exosomes Limites: Humans Langue: En Journal: Cell Rep Année: 2021 Type de document: Article Pays d'affiliation: Canada Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Maladie de Parkinson / Alpha-Synucléine / Exocytose / Exosomes Limites: Humans Langue: En Journal: Cell Rep Année: 2021 Type de document: Article Pays d'affiliation: Canada Pays de publication: États-Unis d'Amérique