Tissue-specific activation of gene expression by the Synergistic Activation Mediator (SAM) CRISPRa system in mice.

Hunt, Charleen; Hartford, Suzanne A; White, Derek; Pefanis, Evangelos; Hanna, Timothy; Herman, Clarissa; Wiley, Jarrell; Brown, Heather; Su, Qi; Xin, Yurong; Voronin, Dennis; Nguyen, Hien; Altarejos, Judith; Crosby, Keith; Haines, Jeffery; Cancelarich, Sarah; Drummond, Meghan; Moller-Tank, Sven; Malpass, Ryan; Buckley, Jacqueline; Del Pilar Molina-Portela, Maria; Droguett, Gustavo; Frendewey, David; Chiao, Eric; Zambrowicz, Brian; Gong, Guochun

Hunt, Charleen; Hartford, Suzanne A; White, Derek; Pefanis, Evangelos; Hanna, Timothy; Herman, Clarissa; Wiley, Jarrell; Brown, Heather; Su, Qi; Xin, Yurong; Voronin, Dennis; Nguyen, Hien; Altarejos, Judith; Crosby, Keith; Haines, Jeffery; Cancelarich, Sarah; Drummond, Meghan; Moller-Tank, Sven; Malpass, Ryan; Buckley, Jacqueline; Del Pilar Molina-Portela, Maria; Droguett, Gustavo; Frendewey, David; Chiao, Eric; Zambrowicz, Brian; Gong, Guochun.

Affiliation

Hunt C; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Hartford SA; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
White D; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Pefanis E; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Hanna T; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Herman C; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Wiley J; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Brown H; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Su Q; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Xin Y; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Voronin D; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Nguyen H; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Altarejos J; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Crosby K; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Haines J; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Cancelarich S; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Drummond M; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Moller-Tank S; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Malpass R; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Buckley J; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Del Pilar Molina-Portela M; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Droguett G; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Frendewey D; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Chiao E; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Zambrowicz B; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Gong G; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA. guochun.gong@regeneron.com.

Nat Commun ; 12(1): 2770, 2021 05 13.

Article de En | MEDLINE | ID: mdl-33986266

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Préalbumine / Activation de la transcription / Systèmes CRISPR-Cas / Hypercholestérolémie / Liposomes Limites: Animals / Humans Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2021 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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