Silylation of Deoxynucleotide Analog Yields an Orally Available Drug with Antileukemia Effects.

Ureshino, Hiroshi; Kurahashi, Yuki; Watanabe, Tatsuro; Yamashita, Satoshi; Kamachi, Kazuharu; Yamamoto, Yuta; Fukuda-Kurahashi, Yuki; Yoshida-Sakai, Nao; Hattori, Naoko; Hayashi, Yoshihiro; Kawaguchi, Atsushi; Tohyama, Kaoru; Okada, Seiji; Harada, Hironori; Ushijima, Toshikazu; Kimura, Shinya

Ureshino, Hiroshi; Kurahashi, Yuki; Watanabe, Tatsuro; Yamashita, Satoshi; Kamachi, Kazuharu; Yamamoto, Yuta; Fukuda-Kurahashi, Yuki; Yoshida-Sakai, Nao; Hattori, Naoko; Hayashi, Yoshihiro; Kawaguchi, Atsushi; Tohyama, Kaoru; Okada, Seiji; Harada, Hironori; Ushijima, Toshikazu; Kimura, Shinya.

Affiliation

Ureshino H; Department of Drug Discovery and Biomedical Sciences, Faculty of Medicine, Saga University, Saga, Japan.
Kurahashi Y; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.
Watanabe T; Department of Drug Discovery and Biomedical Sciences, Faculty of Medicine, Saga University, Saga, Japan.
Yamashita S; Department of Drug Discovery and Biomedical Sciences, Faculty of Medicine, Saga University, Saga, Japan.
Kamachi K; Division of Epigenomics, National Cancer Center Research Institute, Tokyo, Japan.
Yamamoto Y; Department of Drug Discovery and Biomedical Sciences, Faculty of Medicine, Saga University, Saga, Japan.
Fukuda-Kurahashi Y; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.
Yoshida-Sakai N; Department of Drug Discovery and Biomedical Sciences, Faculty of Medicine, Saga University, Saga, Japan.
Hattori N; Department of Drug Discovery and Biomedical Sciences, Faculty of Medicine, Saga University, Saga, Japan.
Hayashi Y; Department of Drug Discovery and Biomedical Sciences, Faculty of Medicine, Saga University, Saga, Japan.
Kawaguchi A; Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.
Tohyama K; Division of Epigenomics, National Cancer Center Research Institute, Tokyo, Japan.
Okada S; Laboratory of Oncology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
Harada H; Center for Comprehensive Community Medicine, Faculty of Medicine, Saga University, Saga, Japan.
Ushijima T; Department of Laboratory Medicine, Kawasaki Medical School, Kurashiki, Japan.
Kimura S; Division of Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto, Japan.

Mol Cancer Ther ; 20(8): 1412-1421, 2021 08.

Article de En | MEDLINE | ID: mdl-34045225

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Silanes / Syndromes myélodysplasiques / Leucémie aigüe myéloïde / Décitabine Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Mol Cancer Ther Sujet du journal: ANTINEOPLASICOS Année: 2021 Type de document: Article Pays d'affiliation: Japon Pays de publication: États-Unis d'Amérique

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