PARP Power: A Structural Perspective on PARP1, PARP2, and PARP3 in DNA Damage Repair and Nucleosome Remodelling.

van Beek, Lotte; McClay, Éilís; Patel, Saleha; Schimpl, Marianne; Spagnolo, Laura; Maia de Oliveira, Taiana

van Beek, Lotte; McClay, Éilís; Patel, Saleha; Schimpl, Marianne; Spagnolo, Laura; Maia de Oliveira, Taiana.

Affiliation

van Beek L; Structure and Biophysics, Discovery Sciences, R&D, AstraZeneca, Cambridge CB4 0WG, UK.
McClay É; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Garscube Campus, University of Glasgow, Glasgow G61 1QQ, UK.
Patel S; Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB4 0WG, UK.
Schimpl M; Structure and Biophysics, Discovery Sciences, R&D, AstraZeneca, Cambridge CB4 0WG, UK.
Spagnolo L; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Garscube Campus, University of Glasgow, Glasgow G61 1QQ, UK.
Maia de Oliveira T; Structure and Biophysics, Discovery Sciences, R&D, AstraZeneca, Cambridge CB4 0WG, UK.

Int J Mol Sci ; 22(10)2021 May 12.

Article de En | MEDLINE | ID: mdl-34066057

Sujet(s)
Mots clés

ADP-ribosylation; DNA damage response; PARP activation; PARP-DNA binding; Poly (ADP-ribose) polymerases 1-3; histone PARylation factor 1; nucleosome remodelling

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Nucléosomes / Poly(ADP-ribose) polymerases / Protéines du cycle cellulaire / Poly (ADP-Ribose) polymerase-1 Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Int J Mol Sci Année: 2021 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: Suisse

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