Categorizing the characteristics of human carcinogens: a need for specificity.

Smith, Carr J; Perfetti, Thomas A; Hayes, A Wallace; Berry, Sir Colin; Trosko, James E; King, Judy A; Goodman, Jay I; Begley, C Glenn; Dayan, Anthony

Smith, Carr J; Perfetti, Thomas A; Hayes, A Wallace; Berry, Sir Colin; Trosko, James E; King, Judy A; Goodman, Jay I; Begley, C Glenn; Dayan, Anthony.

Affiliation

Smith CJ; Albemarle Corporation, 6400 Brindlewood Court, Mobile, AL, 36608, USA. carr.smith@albemarle.com.
Perfetti TA; Perfetti and Perfetti, LLC, Winston-Salem, NC, USA.
Hayes AW; University of South Florida College of Public Health and Institute for Integrative Toxicology, Michigan State University, East Lansing, MI, USA.
Berry SC; Queen Mary, London, UK.
Trosko JE; Department of Pediatrics and Human Development, Michigan State University, East Lansing, MI, USA.
King JA; Department of Pathology and Translational Pathobiology, Louisiana State University Health Shreveport, Shreveport, LA, USA.
Goodman JI; Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, USA.
Begley CG; Independent Biotech Consultant, Victoria, AU, Australia.
Dayan A; Royal College of Physicians, London, UK.

Arch Toxicol ; 95(8): 2883-2889, 2021 08.

Article de En | MEDLINE | ID: mdl-34148101

Sujet(s)
Mots clés

International Agency for Research on Cancer; TKC; TKC broad and lack specificity; TKCs give high rate of false positives; Ten key characteristics of human carcinogens

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Cancérogènes / Carcinogenèse / Tumeurs Type d'étude: Diagnostic_studies / Etiology_studies / Guideline / Risk_factors_studies Limites: Animals / Humans Langue: En Journal: Arch Toxicol Année: 2021 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Allemagne

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