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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop.
Marangoni, Francesco; Zhakyp, Ademi; Corsini, Michela; Geels, Shannon N; Carrizosa, Esteban; Thelen, Martin; Mani, Vinidhra; Prüßmann, Jasper N; Warner, Ross D; Ozga, Aleksandra J; Di Pilato, Mauro; Othy, Shivashankar; Mempel, Thorsten R.
Affiliation
  • Marangoni F; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA 92697, USA; Institute for Immunology, University of
  • Zhakyp A; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA.
  • Corsini M; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA.
  • Geels SN; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA 92697, USA; Institute for Immunology, University of California, Irvine, Irvine, CA 92697, USA.
  • Carrizosa E; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA.
  • Thelen M; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA.
  • Mani V; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA.
  • Prüßmann JN; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA.
  • Warner RD; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA.
  • Ozga AJ; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA.
  • Di Pilato M; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA.
  • Othy S; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA 92697, USA; Institute for Immunology, University of California, Irvine, Irvine, CA 92697, USA.
  • Mempel TR; The Center for Immunology and Inflammatory Diseases (CIID), Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address: tmempel@mgh.harvard.edu.
Cell ; 184(15): 3998-4015.e19, 2021 07 22.
Article de En | MEDLINE | ID: mdl-34157302

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lymphocytes T régulateurs / Rétrocontrôle physiologique / Antigène CTLA-4 / Tumeurs Type d'étude: Risk_factors_studies Limites: Animals / Humans Langue: En Journal: Cell Année: 2021 Type de document: Article Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Lymphocytes T régulateurs / Rétrocontrôle physiologique / Antigène CTLA-4 / Tumeurs Type d'étude: Risk_factors_studies Limites: Animals / Humans Langue: En Journal: Cell Année: 2021 Type de document: Article Pays de publication: États-Unis d'Amérique