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Phase 1 dose-escalation and pharmacokinetic study of regorafenib in paediatric patients with recurrent or refractory solid malignancies.
Geoerger, Birgit; Morland, Bruce; Jiménez, Irene; Frappaz, Didier; Pearson, Andrew D J; Vassal, Gilles; Maeda, Patricia; Kincaide, Jasmine; Mueller, Udo; Schlief, Sarah; Teufel, Michael; Ploeger, Bart A; Cleton, Adriaan; Agostinho, Andrea C; Marshall, Lynley V.
Affiliation
  • Geoerger B; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Université Paris-Saclay, INSERM U1015, Villejuif, France. Electronic address: birgit.geoerger@gustaveroussy.fr.
  • Morland B; Department of Oncology, Birmingham Women's and Children's Hospital, Birmingham, UK.
  • Jiménez I; SIREDO Pediatric Oncology Center, Institut Curie, Paris, France.
  • Frappaz D; Pediatric Department, Centre Léon Bérard, Lyon, France.
  • Pearson ADJ; Children & Young People's Unit, Paediatric and Adolescent Oncology Drug Development Team, The Royal Marsden NHS Foundation Trust and Division of Clinical Studies, Institute of Cancer Research, Sutton, UK.
  • Vassal G; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Université Paris-Saclay, INSERM U1015, Villejuif, France.
  • Maeda P; Oncology, Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Kincaide J; Oncology, Bayer Oy, Espoo, Finland.
  • Mueller U; Department of Statistics, ClinStat GmbH, Cologne, Germany.
  • Schlief S; Medical Affairs and Pharmacovigilance, Bayer AG, Berlin, Germany.
  • Teufel M; Oncology, Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Ploeger BA; Clinical Pharmacometrics, Bayer AG, Berlin, Germany.
  • Cleton A; Translational Medicine, Bayer AG, Berlin, Germany.
  • Agostinho AC; Oncology, Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Marshall LV; Children & Young People's Unit, Paediatric and Adolescent Oncology Drug Development Team, The Royal Marsden NHS Foundation Trust and Division of Clinical Studies, Institute of Cancer Research, Sutton, UK.
Eur J Cancer ; 153: 142-152, 2021 08.
Article de En | MEDLINE | ID: mdl-34157616
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Phénylurées / Pyridines / Tumeurs Type d'étude: Prognostic_studies Limites: Adolescent / Child / Child, preschool / Humans / Infant Langue: En Journal: Eur J Cancer Année: 2021 Type de document: Article
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Phénylurées / Pyridines / Tumeurs Type d'étude: Prognostic_studies Limites: Adolescent / Child / Child, preschool / Humans / Infant Langue: En Journal: Eur J Cancer Année: 2021 Type de document: Article