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A structure and function relationship study to identify the impact of the R721G mutation in the human mitochondrial lon protease.
Sha, Zhou; Montano, Monica M; Rochon, Kristy; Mears, Jason A; Deredge, Daniel; Wintrode, Patrick; Szweda, Luke; Mikita, Natalie; Lee, Irene.
Affiliation
  • Sha Z; Department of Chemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Montano MM; Department of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Rochon K; Department of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Mears JA; Department of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA; Center for Mitochondrial Diseases, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Deredge D; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, 21201, USA.
  • Wintrode P; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, 21201, USA.
  • Szweda L; Department of Internal Medicine, Division of Cardiology, UT Southwestern Medical Center, Dallas, TX, 75390, USA.
  • Mikita N; Department of Chemistry, Case Western Reserve University, Cleveland, OH, 44106, USA; Department of Chemistry, Missouri Western State University, St. Joseph, MO, 64507, USA. Electronic address: nmikita@missouriwestern.edu.
  • Lee I; Department of Chemistry, Case Western Reserve University, Cleveland, OH, 44106, USA. Electronic address: ixl13@case.edu.
Arch Biochem Biophys ; 710: 108983, 2021 10 15.
Article de En | MEDLINE | ID: mdl-34228963

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protease La / Mitochondries Type d'étude: Prognostic_studies Langue: En Journal: Arch Biochem Biophys Année: 2021 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protease La / Mitochondries Type d'étude: Prognostic_studies Langue: En Journal: Arch Biochem Biophys Année: 2021 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique