[Difficulties of cerebral toxoplasmosis diagnosis in a patient with multiple sclerosis and HIV]. / Trudnosti diagnostiki tserebral'nogo toksoplazmoza u patsientki s rasseyannym sklerozom i VICh-infektsiei.
Zh Nevrol Psikhiatr Im S S Korsakova
; 121(6): 76-80, 2021.
Article
de Ru
| MEDLINE
| ID: mdl-34283534
ABSTRACT
Toxoplasmosis is a widespread parasitic disease. It is caused by an intracellular parasite Toxoplasma gondii. It can affect various tissues and organs, forming cysts and continuing to replicate within them. In people with intact immune system, tissue cysts remain in latent state throughout their whole life. However, in cases of cellular immunodeficiency the infection can be reactivated, which leads to secondary generalization of the process. People with HIV most commonly present with cerebral toxoplasmosis. Non-specific neuroimaging signs, as well as absence of pathognomonic symptoms and specific laboratory data lead to difficulties of cerebral toxoplasmosis diagnosis, particularly in the cases with a history of multiple sclerosis that has similar clinical symptoms and brain MRI data suggesting of tumefactive multiple sclerosis image. A clinical case of cerebral toxoplasmosis in a female patient with multiple sclerosis and HIV infection is described.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Toxoplasma
/
Infections à VIH
/
Toxoplasmose cérébrale
/
Sclérose en plaques
Type d'étude:
Diagnostic_studies
Limites:
Female
/
Humans
Langue:
Ru
Journal:
Zh Nevrol Psikhiatr Im S S Korsakova
Sujet du journal:
NEUROLOGIA
/
PSIQUIATRIA
Année:
2021
Type de document:
Article
Pays d'affiliation:
Russie