Prevalence of sleep disturbances and their effects on quality of life in adults with untreated pituitary tumor and meningioma.
J Neurooncol
; 154(2): 179-186, 2021 Sep.
Article
de En
| MEDLINE
| ID: mdl-34304334
ABSTRACT
PURPOSE:
To explore the prevalence of sleep disturbances and their effects on quality of life in adults with pituitary tumor or meningioma.METHODS:
This prospective study included 33 and 44 patients with pituitary tumor and meningioma, respectively. All participants completed a series of valid questionnaires for assessing sleep and quality of life; all participants wore 3-day actigraph prior to related treatment. The actigraph-derived sleep parameters included total sleep time, sleep onset latency, wake after sleep onset, sleep efficiency, and dichotomy index (I < O) value.RESULTS:
The prevalence of insomnia, excessive daytime sleepiness, and poor sleep quality was 46.8%, 6.5%, and 81.8%, respectively. The differences in these sleep parameters between patients with pituitary tumor and those with meningioma were nonsignificant. Only 27 participants completed the actigraphic assessments. The mean I < O value was 95.99%, and nearly 60% participants exhibited circadian rhythm disruption. Sleep quality was the only sleep variable independently correlated with preoperative quality of life, even after adjustments for confounders (B = 0.80, p = 0.02).CONCLUSIONS:
Insomnia, poor sleep quality, and disrupted circadian rhythm are highly prevalent in adults with untreated pituitary tumor or meningioma. Sleep quality independently correlated with quality of life. We indirectly confirmed that tumor location may not be a possible cause of sleep changes.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs de l'hypophyse
/
Troubles de la veille et du sommeil
/
Troubles de l'endormissement et du maintien du sommeil
/
Tumeurs des méninges
/
Méningiome
Type d'étude:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Aspects:
Patient_preference
Limites:
Adult
/
Humans
Langue:
En
Journal:
J Neurooncol
Année:
2021
Type de document:
Article
Pays d'affiliation:
Taïwan