Synthesis, Characterization, Antitumor Potential, BSA and DNA Binding Properties, and Molecular Docking Study of Some Novel 3-Hydroxy-3- Pyrrolin-2-Ones.

Joksimovic, Nenad; Petronijevic, Jelena; Milovic, Emilija; Jankovic, Nenad; Baskic, Dejan; Popovic, Suzana; Todorovic, Danijela; Matic, Sanja; Vranes, Milan; Tot, Aleksandar

Joksimovic, Nenad; Petronijevic, Jelena; Milovic, Emilija; Jankovic, Nenad; Baskic, Dejan; Popovic, Suzana; Todorovic, Danijela; Matic, Sanja; Vranes, Milan; Tot, Aleksandar.

Affiliation

Joksimovic N; Department of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovica 12, Kragujevac 34000, Serbia
Petronijevic J; Department of Sciences, Institute for Information Technologies Kragujevac, University of Kragujevac, Jovana Cvijica bb, Kragujevac 34000, Serbia
Milovic E; Department of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovica 12, Kragujevac 34000, Serbia
Jankovic N; Department of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovica 12, Kragujevac 34000, Serbia
Baskic D; Department of Chemistry, Faculty of Science, University of Kragujevac, Radoja Domanovica 12, Kragujevac 34000, Serbia
Popovic S; Centre for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac 34000, Serbia
Todorovic D; Centre for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac 34000, Serbia
Matic S; Department of Genetics, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac 34000, Serbia
Vranes M; Department of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Svetozara Markovica 69, Kragujevac 34000, Serbia
Tot A; Department of Chemistry, Biochemistry and Environmental Protection, University of Novi Sad, Trg Dositeja Obradovica 3, Novi Sad 21000, Serbia

Med Chem ; 18(3): 337-352, 2022.

Article de En | MEDLINE | ID: mdl-34344294

Sujet(s)
Mots clés

3-hydroxy-3-pyrrolin-2-ones; BSAbinding study; DNA binding study; biological evaluation; mechanisms of cytotoxic activity; molecular docking study

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs / Antinéoplasiques Limites: Humans Langue: En Journal: Med Chem Sujet du journal: QUIMICA Année: 2022 Type de document: Article Pays de publication: Pays-Bas

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