Hybrid lipid core chitosan-TPGS shell nanocomposites as a promising integrated nanoplatform for enhanced oral delivery of sulpiride in depressive disorder therapy.

Mohyeldin, Salma M; Samy, Wael M; Ragab, Doaa; Abdelmonsif, Doaa A; Aly, Rania G; Elgindy, Nazik A

Mohyeldin, Salma M; Samy, Wael M; Ragab, Doaa; Abdelmonsif, Doaa A; Aly, Rania G; Elgindy, Nazik A.

Affiliation

Mohyeldin SM; Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt. Electronic address: salma.eldin@alexu.edu.eg.
Samy WM; Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Ragab D; Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Abdelmonsif DA; Department of Medical Biochemistry, Faculty of Medicine, Alexandria University, Alexandria, Egypt; Centre of Excellence for Research in Regenerative Medicine and Applications (CERRMA), Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Aly RG; Department of Surgical Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Elgindy NA; Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; College of Pharmacy, Arab Academy for Science, Technology & Maritime Transport, Alexandria, Egypt.

Int J Biol Macromol ; 188: 432-449, 2021 Oct 01.

Article de En | MEDLINE | ID: mdl-34375663

Sujet(s)
Mots clés

Chitosan-TPGS; Depression; Nanohybrids; Oral bioavailability; Sulpiride; Toxicity

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Sulpiride / Chitosane / Trouble dépressif / Nanocomposites Limites: Humans Langue: En Journal: Int J Biol Macromol Année: 2021 Type de document: Article

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