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Identification of 6-hydroxy-5-phenyl sulfonylpyrimidin-4(1H)-one APJ receptor agonists.
Tora, George; Jiang, Ji; Bostwick, Jeffrey S; Gargalovic, Peter S; Onorato, Joelle M; Luk, Chiuwa E; Generaux, Claudia; Xu, Carrie; Galella, Michael A; Wang, Tao; He, Yan; Wexler, Ruth R; Finlay, Heather J.
Affiliation
  • Tora G; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Jiang J; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States. Electronic address: ji.jiang@bms.com.
  • Bostwick JS; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Gargalovic PS; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Onorato JM; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Luk CE; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Generaux C; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Xu C; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Galella MA; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Wang T; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • He Y; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Wexler RR; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
  • Finlay HJ; Department of Discovery Chemistry, Bristol-Myers Squibb, Research and Development, PO Box 5400, Princeton, NJ 08543-5400, United States.
Bioorg Med Chem Lett ; 50: 128325, 2021 10 15.
Article de En | MEDLINE | ID: mdl-34403724
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Agents cardiovasculaires / Protéines et peptides de signalisation intercellulaire / Récepteur de l'apeline Type d'étude: Diagnostic_studies / Prognostic_studies Limites: Animals / Humans Langue: En Journal: Bioorg Med Chem Lett Sujet du journal: BIOQUIMICA / QUIMICA Année: 2021 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Agents cardiovasculaires / Protéines et peptides de signalisation intercellulaire / Récepteur de l'apeline Type d'étude: Diagnostic_studies / Prognostic_studies Limites: Animals / Humans Langue: En Journal: Bioorg Med Chem Lett Sujet du journal: BIOQUIMICA / QUIMICA Année: 2021 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni