Uridine treatment prevents myocardial injury in rat models of acute ischemia and ischemia/reperfusion by activating the mitochondrial ATP-dependent potassium channel.

Krylova, Irina B; Selina, Elena N; Bulion, Valentina V; Rodionova, Olga M; Evdokimova, Natalia R; Belosludtseva, Natalia V; Shigaeva, Maria I; Mironova, Galina D

Krylova, Irina B; Selina, Elena N; Bulion, Valentina V; Rodionova, Olga M; Evdokimova, Natalia R; Belosludtseva, Natalia V; Shigaeva, Maria I; Mironova, Galina D.

Affiliation

Krylova IB; Department of Neuropharmacology, Federal State Budgetary Scientific Institution, Institute of Experimental Medicine, St. Petersburg, Russia, 197376. irinakrylova@mail.ru.
Selina EN; Department of Neuropharmacology, Federal State Budgetary Scientific Institution, Institute of Experimental Medicine, St. Petersburg, Russia, 197376.
Bulion VV; Department of Neuropharmacology, Federal State Budgetary Scientific Institution, Institute of Experimental Medicine, St. Petersburg, Russia, 197376.
Rodionova OM; Department of Neuropharmacology, Federal State Budgetary Scientific Institution, Institute of Experimental Medicine, St. Petersburg, Russia, 197376.
Evdokimova NR; Department of Neuropharmacology, Federal State Budgetary Scientific Institution, Institute of Experimental Medicine, St. Petersburg, Russia, 197376.
Belosludtseva NV; Laboratory of Mitochondrial Transport, Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Pushchino, Moscow Region, Russia, 142290.
Shigaeva MI; Laboratory of Mitochondrial Transport, Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Pushchino, Moscow Region, Russia, 142290.
Mironova GD; Laboratory of Mitochondrial Transport, Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Pushchino, Moscow Region, Russia, 142290. mironova40@mail.ru.

Sci Rep ; 11(1): 16999, 2021 08 20.

Article de En | MEDLINE | ID: mdl-34417540

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Uridine / Lésion de reperfusion myocardique / Canaux potassiques / Myocarde Type d'étude: Etiology_studies Limites: Animals Langue: En Journal: Sci Rep Année: 2021 Type de document: Article Pays de publication: Royaume-Uni

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