Splenomegaly: Diagnosis and Management in Adults.
Am Fam Physician
; 104(3): 271-276, 2021 Sep 01.
Article
de En
| MEDLINE
| ID: mdl-34523897
ABSTRACT
Splenomegaly can be due to several mechanisms but is almost always a sign of a systemic condition. Patient habits, travel, and medical conditions can increase risk of splenomegaly and suggest etiology. Symptoms can suggest infectious, malignant, hepatic, or hematologic causes. Physical examination will typically reveal splenomegaly, but abdominal ultrasonography is recommended for confirmation. Physical examination should also assess for signs of systemic illness, liver disease, and anemia or other hematologic issues. The most common causes of splenomegaly in the United States are liver disease, malignancy, and infection. Except for apparent causes such as infectious mononucleosis, basic laboratory analysis and ultrasonography are the first-line steps in determining etiology. Malaria and schistosomiasis are common in tropical regions, where as many as 80% of people may have splenomegaly. Management of splenomegaly involves treating the underlying disease process. Splenectomies and spleen reduction therapies are sometimes performed. Any patient with limited splenic function requires increased vaccination and prophylactic antibiotics for procedures involving the respiratory tract. Acute infections, anemia, and splenic rupture are the most common complications of splenomegaly, and people with splenomegaly should refrain from participating in contact sports to decrease risk of rupture.
Recherche sur Google
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Splénomégalie
Type d'étude:
Diagnostic_studies
/
Etiology_studies
Limites:
Humans
Langue:
En
Journal:
Am Fam Physician
Année:
2021
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique