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A Vimentin-Targeting Oral Compound with Host-Directed Antiviral and Anti-Inflammatory Actions Addresses Multiple Features of COVID-19 and Related Diseases.
Li, Zhizhen; Wu, Jianping; Zhou, Ji; Yuan, Baoshi; Chen, Jiqiao; Wu, Wanchen; Mo, Lian; Qu, Zhipeng; Zhou, Fei; Dong, Yingying; Huang, Kai; Liu, Zhiwei; Wang, Tao; Symmes, Deebie; Gu, Jingliang; Sho, Eiketsu; Zhang, Jingping; Chen, Ruihuan; Xu, Ying.
Affiliation
  • Li Z; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Su Genomic Resource Center, Medical School of Soochow University, Suzhou, Jiangsu, China.
  • Wu J; Laboratory Animal Center, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
  • Zhou J; Luoda Biosciences, Inc., Chuzhou, Anhui, China.
  • Yuan B; Institute of Biology and Medical Sciences, Medical School of Soochow University, Suzhou, Jiangsu, China.
  • Chen J; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Su Genomic Resource Center, Medical School of Soochow University, Suzhou, Jiangsu, China.
  • Wu W; KCI Biotech (Suzhou) Inc., Suzhou, Jiangsu, China.
  • Mo L; Joinn Laboratories (Suzhou), Co., Ltd., Suzhou, Jiangsu, China.
  • Qu Z; Aluda Pharmaceuticals, Inc., Menlo Park, California, USA.
  • Zhou F; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Su Genomic Resource Center, Medical School of Soochow University, Suzhou, Jiangsu, China.
  • Dong Y; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Su Genomic Resource Center, Medical School of Soochow University, Suzhou, Jiangsu, China.
  • Huang K; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Su Genomic Resource Center, Medical School of Soochow University, Suzhou, Jiangsu, China.
  • Liu Z; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Su Genomic Resource Center, Medical School of Soochow University, Suzhou, Jiangsu, China.
  • Wang T; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Su Genomic Resource Center, Medical School of Soochow University, Suzhou, Jiangsu, China.
  • Symmes D; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Su Genomic Resource Center, Medical School of Soochow University, Suzhou, Jiangsu, China.
  • Gu J; Aluda Pharmaceuticals, Inc., Menlo Park, California, USA.
  • Sho E; Joinn Laboratories (Suzhou), Co., Ltd., Suzhou, Jiangsu, China.
  • Zhang J; KCI Biotech (Suzhou) Inc., Suzhou, Jiangsu, China.
  • Chen R; Institute of Biology and Medical Sciences, Medical School of Soochow University, Suzhou, Jiangsu, China.
  • Xu Y; Luoda Biosciences, Inc., Chuzhou, Anhui, China.
mBio ; 12(5): e0254221, 2021 10 26.
Article de En | MEDLINE | ID: mdl-34634931
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Antiviraux / Composés chimiques organiques / Vimentine / Glycoprotéine de spicule des coronavirus / COVID-19 / Traitements médicamenteux de la COVID-19 / Anti-inflammatoires Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: MBio Année: 2021 Type de document: Article Pays d'affiliation: Chine Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Antiviraux / Composés chimiques organiques / Vimentine / Glycoprotéine de spicule des coronavirus / COVID-19 / Traitements médicamenteux de la COVID-19 / Anti-inflammatoires Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: MBio Année: 2021 Type de document: Article Pays d'affiliation: Chine Pays de publication: États-Unis d'Amérique