Effects of radiation on tumor vasculature.
Mol Carcinog
; 61(2): 165-172, 2022 02.
Article
de En
| MEDLINE
| ID: mdl-34644811
ABSTRACT
Radiation has been utilized as a direct cytotoxic tumorcidal modality, however, the effect of radiation on tumor vasculature influences response to anticancer therapies. Although numerous reports have demonstrated vascular changes in irradiated tumors, the findings and implications are extensive and at times contradictory depending on the radiation dose, timing, and models used. In this review, we focus on the radiation-mediated effects on tumor vasculature with respect to doses used, timing postradiation, vasculogenesis, adhesion molecule expression, permeability, and pericyte coverage, including the latest findings.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tumeurs
/
Antinéoplasiques
Type d'étude:
Prognostic_studies
Limites:
Humans
Langue:
En
Journal:
Mol Carcinog
Sujet du journal:
BIOLOGIA MOLECULAR
/
NEOPLASIAS
Année:
2022
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique