Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection.

Zhou, Zhuo; Zhang, Xinyi; Lei, Xiaobo; Xiao, Xia; Jiao, Tao; Ma, Ruiyi; Dong, Xiaojing; Jiang, Qi; Wang, Wenjing; Shi, Yujin; Zheng, Tian; Rao, Jian; Xiang, Zichun; Ren, Lili; Deng, Tao; Jiang, Zhengfan; Dou, Zhixun; Wei, Wensheng; Wang, Jianwei

Zhou, Zhuo; Zhang, Xinyi; Lei, Xiaobo; Xiao, Xia; Jiao, Tao; Ma, Ruiyi; Dong, Xiaojing; Jiang, Qi; Wang, Wenjing; Shi, Yujin; Zheng, Tian; Rao, Jian; Xiang, Zichun; Ren, Lili; Deng, Tao; Jiang, Zhengfan; Dou, Zhixun; Wei, Wensheng; Wang, Jianwei.

Affiliation

Zhou Z; Biomedical Pioneering Innovation Center, Beijing Advanced Innovation Center for Genomics, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China. z
Zhang X; Biomedical Pioneering Innovation Center, Beijing Advanced Innovation Center for Genomics, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.
Lei X; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Xiao X; Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Jiao T; Christophe Merieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Ma R; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Dong X; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Jiang Q; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Wang W; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Shi Y; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Zheng T; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Rao J; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Xiang Z; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Ren L; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Deng T; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Jiang Z; Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Dou Z; Christophe Merieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Wei W; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.
Wang J; Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730, Beijing, P.R. China.

Signal Transduct Target Ther ; 6(1): 382, 2021 11 03.

Article de En | MEDLINE | ID: mdl-34732709

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Chromatine / Cytoplasme / SARS-CoV-2 / COVID-19 / Immunité innée / Nucleotidyltransferases Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Signal Transduct Target Ther Année: 2021 Type de document: Article Pays de publication: Royaume-Uni

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