Optimal Medical Therapy as First-Line Therapy for Chronic Coronary Syndromes: Lessons from COURAGE, BARI 2D, FAME 2, and ISCHEMIA.
Cardiovasc Drugs Ther
; 36(5): 1039-1045, 2022 10.
Article
de En
| MEDLINE
| ID: mdl-34767134
ABSTRACT
The chronic coronary syndromes (CCS) include patients with a classic history of angina pectoris in the presence of either risk factors for or known atherosclerotic coronary artery disease. Randomized, controlled trials conducted in the optimal medical therapy (OMT) era have convincingly demonstrated that adherence to the outdated paradigm focused on treatment of obstructive coronary disease with initial revascularization fails to reduce death or myocardial infarction and inconsistently reduces angina symptoms. Rather, OMT reduces events and improves symptoms and should be considered first-line treatment for patients with CCS.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Maladie des artères coronaires
/
Courage
/
Infarctus du myocarde
Type d'étude:
Clinical_trials
/
Diagnostic_studies
/
Risk_factors_studies
Limites:
Humans
Langue:
En
Journal:
Cardiovasc Drugs Ther
Sujet du journal:
ANGIOLOGIA
/
CARDIOLOGIA
/
TERAPIA POR MEDICAMENTOS
Année:
2022
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique